Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos (URJC), Madrid, Spain.
Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos (URJC), Madrid, Spain.
Diabetes Metab Syndr. 2021 Jul-Aug;15(4):102159. doi: 10.1016/j.dsx.2021.05.032. Epub 2021 Jun 1.
To propose an integrative model for post-COVID symptoms by considering the absence/presence of previous symptomatology.
We searched different databases for original articles and reviews on post-COVID symptoms.
The first consideration is to define which symptoms are of "new-onset" (symptoms never experienced by a patient before COVID-19 and experienced the first time after) and which symptoms are "exacerbated" (symptoms experienced by a patient prior to COVID-19 but aggravated later) after infection. The second consideration includes defining "persistent" (symptoms experienced at the acute phase and continuing after without remission period) and "delayed-onset" (symptoms not experienced at the acute phase of the infection but appearing after a "latency period"). This model integrates predisposing individual factors, biological factors associated to the severity of disease, hospitalization/treatment factors, and outbreak surrounding factors which may promote post-COVID.
Since current literature on post-COVID is heterogeneous, this integrative model could help to a better characterization of long-COVID.
通过考虑既往症状的有无，提出一种针对新冠后症状的综合模型。
我们在不同的数据库中搜索了关于新冠后症状的原始文章和综述。
首先要定义哪些症状是“新出现的”（患者在感染 COVID-19 之前从未经历过的症状，并且是第一次经历），哪些症状是“加重的”（患者在感染 COVID-19 之前经历过的症状，但后来加重了）。其次，包括定义“持续的”（在急性期经历的症状，并且没有缓解期继续存在）和“延迟出现的”（在感染的急性期未经历的症状，但在“潜伏期”后出现）。该模型综合了易患个体因素、与疾病严重程度相关的生物学因素、住院/治疗因素以及可能促进新冠后出现的疫情周边因素。
由于目前关于新冠后症状的文献存在异质性，这种综合模型可以帮助更好地描述长新冠。
