Kuntima Diasiama Pablo Diangienda, Moningo Molamba Dieudonné, Makulo Rissasy Jean-Robert, Sumaili Kiswaya Ernest, Mafuta Musalu Éric, Ngoma Alain, Loposso Nkumu Mathieu, Punga-Maole Augustin, Lwa Nkandi Simon Lufuma, Haymann Jean-Philippe, Daudon Michel
Service d'urologie, cliniques universitaires de Kinshasa, BP 123, Kinshasa 11, République démocratique du Congo.
Service d'urologie, cliniques universitaires de Kinshasa, BP 123, Kinshasa 11, République démocratique du Congo.
Nephrol Ther. 2021 Oct;17(6):441-450. doi: 10.1016/j.nephro.2021.04.002. Epub 2021 Jun 27.
To compare the chemical composition of the upper and lower urinary tract stones in Congolese patients, and to identify factors associated with the different types of stones. Stones from 119 patients originating from the upper tract and 75 from the lower tract were analyzed by infrared spectrophotometry. Among 119 patients with upper tract stones, age ranged from 10 to 81 years with a mean (SD) of 45.8 (13.6) years; males were the majority (55.5%). The main types of stones identified were whewellite (79%). For the 75 patients with lower apparatus stones, age ranged from 4 to 87 years with a mean (SD) of 51.6 (21.6) years; the majority were males (89.3%). The main types of stones were whewellite (44%) and anhydrous uric acid (22.7%). Overall, the factors associated with calcium oxalate included: site [4.95 (95% CI 2.35-10.44)] and diameter [3.03 (95% CI 1.45-6.25)]; patient's place of residence [0.05 (95% CI 0.01-0.29)] was associated with calcium phosphate. Infection stones were associated with; site [0.19 (95% CI 0.06-0.63)] and diameter [0.10 (95% CI 0.03-0.38)]. Finally, age 0.26 (95% CI 0.09-0.71) and stone site [0.23 (95% CI 0.07-0.68)] were associated with uric stones. The epidemiological and chemical profile of upper and lower tract stones were different. Several factors were associated with the chemical and crystalline composition of stones in the Democratic Republic of Congo.
比较刚果患者上尿路结石和下尿路结石的化学成分，并确定与不同类型结石相关的因素。采用红外分光光度法分析了119例上尿路结石患者和75例下尿路结石患者的结石。119例上尿路结石患者年龄在10至81岁之间，平均（标准差）为45.8（13.6）岁；男性占多数（55.5%）。鉴定出的主要结石类型是草酸钙（79%）。75例下尿路结石患者年龄在4至87岁之间，平均（标准差）为51.6（21.6）岁；大多数为男性（89.3%）。主要结石类型是草酸钙（44%）和无水尿酸（22.7%）。总体而言，与草酸钙相关的因素包括：结石部位[4.95（95%置信区间2.35 - 10.44）]和直径[3.03（95%置信区间1.45 - 6.25）]；患者居住地[0.05（95%置信区间0.01 - 0.29）]与磷酸钙相关。感染性结石与以下因素相关：结石部位[0.19（95%置信区间0.06 - 0.63）]和直径[0.10（95%置信区间0.03 - 0.38）]。最后，年龄0.26（95%置信区间0.09 - 0.71）和结石部位[0.23（95%置信区间0.07 - 0.68）]与尿酸结石相关。上尿路结石和下尿路结石的流行病学和化学特征不同。在刚果民主共和国，有几个因素与结石的化学和晶体成分相关。
