Gandolfo Mariana Silva, Denninghoff Valeria, Avagnina Alejandra, Adler Lidia Isabel
Faculty of Dentistry, University of Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
CONICET, Ciudad Autónoma de Buenos Aires, Argentina.
BMJ Case Rep. 2021 Jun 29;14(6):e240944. doi: 10.1136/bcr-2020-240944.
Metastases derived from primary tumours distant to the oral and maxillofacial region account for only 1% of all malignancies at that location, usually with a poor prognosis. In women, the primary tumours that most frequently metastasise to the oral cavity are breast adenocarcinomas affecting the jawbones and soft tissues (41% and 24%, respectively), followed by adrenal glands and female genital organs to the jawbones (8%), and female genital organs to the soft tissues (15%). Metastatic tumours of the mouth are a challenging diagnosis because of their exceptional occurrence. We report on the case of an 83-year-old woman who consulted for a bleeding ulcerated tumour on the floor of the mouth. A biopsy-confirmed metastasis of an adenocarcinoma of Müllerian origin. The oral lesion was the first sign of undetected cancer. The patient agreed to surgical resection and was further referred to palliative care for her symptoms.
源自口腔颌面区域以外原发肿瘤的转移瘤仅占该部位所有恶性肿瘤的1%,通常预后较差。在女性中,最常转移至口腔的原发肿瘤是影响颌骨和软组织的乳腺腺癌(分别为41%和24%),其次是肾上腺和女性生殖器官转移至颌骨(8%),以及女性生殖器官转移至软组织(15%)。口腔转移性肿瘤因其罕见性而诊断具有挑战性。我们报告了一例83岁女性患者,她因口底出血性溃疡肿瘤前来就诊。活检证实为苗勒管来源腺癌的转移瘤。口腔病变是未被发现癌症的首个迹象。患者同意手术切除,并因其症状被进一步转诊至姑息治疗。