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口腔癌中慢性机械刺激的特征

Characterization of Chronic Mechanical Irritation in Oral Cancer.

作者信息

Lazos Jerónimo P, Piemonte Eduardo D, Lanfranchi Hector Eduardo, Brunotto Mabel N

机构信息

Oral Medicine Department, Dentistry College, Universidad Nacional de Córdoba, Av. Haya de la Torre s/n, Ciudad Universitaria 5000, Córdoba, Argentina.

Oral Medicine Department, Dentistry College, Universidad de Buenos Aires, Buenos Aires, Argentina.

出版信息

Int J Dent. 2017;2017:6784526. doi: 10.1155/2017/6784526. Epub 2017 Apr 6.

Abstract

. Oral mucosa could host many lesions originated by chronic mechanical irritation (CMI) from teeth or dentures, and it has been proposed as risk factor for oral cancer. Nevertheless, the features of CMI factors in oral cancer and other lesions are not assessed. The aim of this study is to describe CMI features regarding type (dental, prosthetic, and/or functional), localization, and time span. . Three groups were studied in this cross-sectional study: Oral Cancer (OC); Chronic Traumatic Ulcer (CTU); and Benign Irritative Mechanical Lesions (BIML). All sources of mechanical irritation were included: dental, prosthetic, and functional. . 285 patients (176 females, 109 males) were studied: OC = 38, CTU = 44, and BIML = 203. The most frequent CMI factor was dental, followed by functional and prosthetic in all groups; 76.5% ( = 218) presented functional factors. Buccal mucosa (45%) and tongue (42%) were the most affected sites. Time of action of CMI displayed statistically significant differences between BIML, CTU, and OC groups, with a mean of 21, 33, and 49 months, respectively. . CMI should be properly recorded with as much detail as alcohol and tobacco consumption. CMI associated lesions are produced by dental or prosthetic factors, usually in relation to functional factors, involving mainly tongue and buccal mucosa.

摘要

口腔黏膜可能存在许多由牙齿或假牙的慢性机械刺激(CMI)引发的病变,并且它已被认为是口腔癌的危险因素。然而,口腔癌和其他病变中CMI因素的特征尚未得到评估。本研究的目的是描述CMI在类型(牙齿、修复体和/或功能方面)、定位和时间跨度方面的特征。

在这项横断面研究中对三组进行了研究

口腔癌(OC);慢性创伤性溃疡(CTU);以及良性刺激性机械性病变(BIML)。所有机械刺激源都包括在内:牙齿、修复体和功能方面的。

对285名患者(176名女性,109名男性)进行了研究:OC组38例,CTU组44例,BIML组203例。最常见的CMI因素是牙齿方面的,其次是功能和修复体方面的,在所有组中都是如此;76.5%(n = 218)存在功能方面的因素。颊黏膜(45%)和舌(42%)是受影响最严重的部位。CMI的作用时间在BIML、CTU和OC组之间显示出统计学上的显著差异,平均分别为21、33和49个月。

CMI应像记录饮酒和吸烟情况一样详细地进行记录。与CMI相关联的病变是由牙齿或修复体因素引起的,通常与功能因素有关,主要累及舌和颊黏膜。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7da0/5397630/23850180e756/IJD2017-6784526.001.jpg

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