越南儿童严重复发性肺炎：潜在病因及临床特征
Severe recurrent pneumonia in children: Underlying causes and clinical profile in Vietnam.
作者信息
Hoang Kim Lam, Ta Anh Tuan, Pham Van Thang
机构信息
Department of Pediatrics, Hanoi Medical University, Ton That Tung, Hanoi, Viet Nam.
Vietnam National Children's Hospital, La Thanh, Hanoi, Viet Nam.
出版信息
Ann Med Surg (Lond). 2021 Jun 9;67:102476. doi: 10.1016/j.amsu.2021.102476. eCollection 2021 Jul.
BACKGROUND
There is still limited data on severe recurrent pneumonia in children, especially in developing countries as Vietnam. This study was conducted to identify the underlying causes and clinical profile of children with severe recurrent pneumonia admitted to the Pediatric Intensive Care Unit (PICU), National Children's Hospital.
METHODS
This was a prospective and descriptive study on 110 children with severe pneumonia admitted to the PICU from November 2019 to August 2020. Data were collected to investigate the clinical profile and underlying diseases.
RESULTS
Severe recurrent pneumonia accounted for 29.4%. Underlying causes were diagnosed in 91.8% of sRP children, in which the most common causes were abnormalities in respiratory, cardiovascular system and immune disorders. 74.5% of sRP children admitted to ICU had been previously intubated or ventilated, 34.5% had shock, 7.3% had multiple organ failure. Recurrent lesions on chest x-ray in the same lobe accounted for 18.2%.
CONCLUSIONS
The majority of patients with severe recurrent pneumonia had an underlying disease. Comprehensive management is necessary for severe recurrent pneumonia.
背景
关于儿童重症复发性肺炎的数据仍然有限，尤其是在越南等发展中国家。本研究旨在确定入住国家儿童医院儿科重症监护病房（PICU）的重症复发性肺炎患儿的潜在病因和临床特征。
方法
这是一项对2019年11月至2020年8月入住PICU的110例重症肺炎患儿进行的前瞻性描述性研究。收集数据以调查临床特征和潜在疾病。
结果
重症复发性肺炎占29.4%。91.8%的重症复发性肺炎患儿被诊断出潜在病因，其中最常见的病因是呼吸、心血管系统异常和免疫紊乱。入住ICU的重症复发性肺炎患儿中，74.5%曾接受过插管或机械通气，34.5%发生过休克，7.3%出现多器官功能衰竭。胸部X光片显示同一肺叶反复出现病变的占18.2%。
结论
大多数重症复发性肺炎患者有潜在疾病。重症复发性肺炎需要综合管理。
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