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一名重型β地中海贫血患者的输血后高溶血综合征

Post-transfusion hyperhemolysis syndrome in a patient with beta thalassemia major.

作者信息

Kasinathan Ganesh, Sathar Jameela

机构信息

Department of Haematology Ampang Hospital Ampang Malaysia.

出版信息

Clin Case Rep. 2021 Jun 22;9(6):e04226. doi: 10.1002/ccr3.4226. eCollection 2021 Jun.

Abstract

Hyperhemolysis syndrome (HS) is characterized by the occurrence of severe anemia with post-transfusion hemoglobin and hematocrit levels being markedly lower than those present prior to transfusion. A high index of suspicion of HS in a multi-transfused thalassemia patient allows prompt institution of therapy resulting in improved survival outcome.

摘要

高溶血综合征(HS)的特征是出现严重贫血,输血后血红蛋白和血细胞比容水平明显低于输血前。对多次输血的地中海贫血患者高度怀疑HS,可促使及时进行治疗,从而改善生存结局。

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本文引用的文献

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Hyperhemolysis syndrome complicating pregnancy in homozygous δβ-thalassemia.
Hemoglobin. 2012;36(2):183-5. doi: 10.3109/03630269.2011.649150. Epub 2012 Jan 12.
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Hyperhemolysis syndrome in sickle cell disease.镰状细胞病中的高溶血综合征
Expert Rev Hematol. 2009 Apr;2(2):111-5. doi: 10.1586/ehm.09.2.
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Severe neonatal hemolysis due to a maternal antibody to the low-frequency Rh antigen C(w).
Am J Perinatol. 2006 May;23(4):213-7. doi: 10.1055/s-2006-934098. Epub 2006 Apr 4.

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