Middle Cerebral Artery Duplication: A Near Miss for Stroke Thrombectomy.

Middle cerebral artery (MCA) duplication is a rare anatomical arrangement where an anomalous MCA arises from the distal end of the internal carotid artery. If occluded, a duplicated MCA can present with significant deficits comparable to an occlusion of the M2 vessel without obvious findings on vessel imaging via computed tomography angiography (CTA) or magnetic resonance angiography. A female in her 30s with no past medical history presented with suspected acute stroke 8 hours after last known normal-featuring new-onset right-sided weakness, facial droop, and slurred speech, which corresponds to a National Institutes of Health Stroke Scale score of 13. Head CTA was interpreted as preserved patency of intracranial vessels. CT perfusion was suggestive of a large area of penumbra. Emergent cerebral angiography demonstrated MCA duplication on the left side with proximal occlusion of the M1 branch supplying the traditional M2 territory. Mechanical thrombectomy achieved grade TICI 2b reperfusion. Throughout her hospital stay, her aphasia started to resolve, and the patient was discharged to inpatient rehabilitation. This case presents a diagnostic challenge and learning point in identifying similar patients in the future. We suggest the clinician, given a high clinical suspicion for large vessel occlusion, even if CTA is negative, to continue with CT perfusion to not miss stroke in patients with MCA duplication. If CT perfusion shows substantial deficit in an MCA distribution, one must consider that the patient may have an MCA duplication.