Li Zhenjun, Jiang Jiafu, Ruan Xiangdong, Tong Yigang, Xu Shuai, Han Lichao, Xu Jianguo
State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, PR China.
State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China.
J Biosaf Biosecur. 2021 Jun;3(1):51-55. doi: 10.1016/j.jobb.2021.06.002. Epub 2021 Jun 24.
The origin of SARS-CoV-2 is still an unresolved mystery. In this study, we systematically reviewed the main research progress of wild animals carrying virus highly homologous to SARS-CoV-2 and analyzed the natural foci characteristics of SARS-CoV-2. The complexity of SARS-CoV-2 origin in wild animals and the possibility of SARS-CoV-2 long-term existence in human populations are also discussed. The joint investigation of corona virus carried by wildlife, as well as the ecology and patho-ecology of bats and other wildlife, are key measures to further clarify the characteristics of natural foci of SARS-CoV-2 and actively defend against future outbreaks of emerging zoonotic diseases.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的起源仍是一个未解之谜。在本研究中，我们系统回顾了携带与SARS-CoV-2高度同源病毒的野生动物的主要研究进展，并分析了SARS-CoV-2的自然疫源地特征。还讨论了SARS-CoV-2在野生动物中起源的复杂性以及SARS-CoV-2在人群中长期存在的可能性。对野生动物携带的冠状病毒以及蝙蝠和其他野生动物的生态学和病理生态学进行联合调查，是进一步阐明SARS-CoV-2自然疫源地特征并积极防范未来新发人畜共患病疫情的关键措施。
