Division of Plastic Surgery, UC San Diego.
Rady Children's Hospital.
J Craniofac Surg. 2021 Oct 1;32(7):2373-2378. doi: 10.1097/SCS.0000000000007831.
Unilateral coronal craniosynostosis (UCS) is the third most prevalent form of craniosynostosis. Traditional treatment of UCS has been achieved with fronto-orbital advancement and cranial vault remodeling (FOAR), but utilization of cranial distraction osteogenesis (DO) techniques has increased. This study aims to compare perioperative complications and reoperation trends in FOAR versus DO techniques at a single institution.
An Institutional Review Board-approved retrospective review was performed from January 1999 to November 2018 at a single institution. Patients were those that have undergone FOAR or DO with an anterior rotational flap technique as previously described. Indications for secondary procedures included: contour deformities, relapse, surgical site infection, and persistent cranial defects.
Eighty-one patients with UCS were identified, 64 patients underwent FOAR and 17 patients underwent DO. When perioperative characteristics were compared, patients who underwent DO were younger in age, however, there was no significant difference in transfusion requirement or length of stay between patient cohorts. Surgery time was increased in DO patients. When perioperative complications were compared, more intraoperative dural tears were observed in the FOAR cohort. When unplanned reoperation rates were compared, patients who had undergone FOAR had a statistically significant higher reoperation rates at 5 years of follow up. When including routine distractor removal as a reoperation, reoperative rate was increased in the DO cohort. No difference in reoperation rates was noted at 5 years following index operation.
The safety profile of DO is similar to that of traditional FOAR techniques for treatment of UCS. Longer-term follow-up studies are needed to elucidate whether outcomes are durable, but the unplanned reoperation rate in DO is less than that of FOAR at 5 years and presents several advantages that warrants its use in patients with UCS.
单侧冠状缝早闭(UCS)是第三大常见的颅缝早闭类型。传统的 UCS 治疗方法是额眶前移和颅盖重塑(FOAR),但颅牵张成骨(DO)技术的应用有所增加。本研究旨在比较单中心 FOAR 与 DO 技术的围手术期并发症和再次手术趋势。
对单中心 1999 年 1 月至 2018 年 11 月的一项回顾性研究进行了机构审查委员会(IRB)批准。患者为接受过 FOAR 或 DO 治疗的患者,采用之前描述的前旋转皮瓣技术。二次手术的指征包括:轮廓畸形、复发、手术部位感染和持续的颅骨缺损。
共确定了 81 例 UCS 患者,其中 64 例行 FOAR,17 例行 DO。当比较围手术期特征时,DO 组患者年龄较小,但两组患者的输血需求或住院时间无显著差异。DO 患者的手术时间增加。当比较围手术期并发症时,FOAR 组术中发现更多硬脑膜撕裂。当比较非计划性再次手术率时,FOAR 组在 5 年随访时有统计学意义更高的再次手术率。包括常规牵开器去除作为再次手术时,DO 组的再次手术率增加。在指数手术后 5 年,再次手术率无差异。
DO 的安全性与传统 FOAR 技术治疗 UCS 相似。需要进行长期随访研究以阐明结果是否持久,但 DO 的非计划性再次手术率在 5 年内低于 FOAR,并且具有几个优点,值得在 UCS 患者中使用。