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一项关于冠状缝颅缝早闭畸形矫正后斜视发生率的队列研究:常规双侧额眶前移术与额眶部牵引成骨术的比较。

A Cohort Study of Strabismus Rates Following Correction of the Unicoronal Craniosynostosis Deformity: Conventional Bilateral Fronto-Orbital Advancement Versus Fronto-Orbital Distraction Osteogenesis.

机构信息

Division of Plastic Surgery, The University of Pennsylvania and the Children's Hospital of Philadelphia, Philadelphia, PA.

出版信息

J Craniofac Surg. 2021 Oct 1;32(7):2362-2365. doi: 10.1097/SCS.0000000000007773.

Abstract

BACKGROUND

The purpose of this prospective study is to compare perioperative morbidity and strabismus rates between traditional fronto-orbital advancement reconstruction (FOAR) and fronto-orbital distraction osteogenesis (FODO) in unicoronal craniosynostosis (UCS).

METHOD

A consecutive group of 15 patients undergoing FODO for isolated UCS were compared to a contemporaneous group of 15 patients undergoing traditional FOAR for UCS. Patient age, operative time, blood loss, blood replacement, technical details of the surgery, length of stay, complications, and strabismus rates were documented and compared statistically using chi-square and Student t test with a significance value of 0.05.

RESULTS

The 15 patients undergoing FODO were younger (6.3 and 9.8 months, P < 0.05), experienced less operative time for the initial procedure (111 versus 190 minutes, P < 0.01), less blood loss (26% versus 50% of total blood volume, P < 0.01), and less blood replacement (40% versus 60% of total blood volume, P < 0.05). One patient in the FODO group experienced a new-onset strabismus postoperatively compared with 5 in the FOAR group (P < 0.05). There were no complications requiring a return to the operating room in either group.

CONCLUSIONS

Fronto-orbital distraction osteogenesis for the treatment of isolated UCS is associated with a favorable perioperative morbidity profile and a decreased incidence of postoperative strabismus compared with traditional FOAR. These positive factors are tempered by the need for an additional procedure for removal of the device and lack of long-term outcomes data on the technique.

摘要

背景

本前瞻性研究旨在比较传统额眶前移重建(FOAR)和额眶牵引成骨(FODO)治疗单冠状缝早闭(UCS)的围手术期发病率和斜视率。

方法

将 15 例接受 FODO 治疗的孤立性 UCS 患者与同期接受传统 FOAR 治疗的 15 例 UCS 患者进行比较。记录患者年龄、手术时间、失血量、输血量、手术技术细节、住院时间、并发症和斜视率,并使用卡方检验和 Student t 检验进行统计学比较,显著性水平为 0.05。

结果

15 例接受 FODO 的患者年龄较小(6.3 和 9.8 个月,P<0.05),初次手术时间较短(111 分钟与 190 分钟,P<0.01),失血量较少(总出血量的 26%与 50%,P<0.01),输血量较少(总出血量的 40%与 60%,P<0.05)。与 FOAR 组的 5 例相比,FODO 组有 1 例患者术后出现新发性斜视(P<0.05)。两组均无需要返回手术室的并发症。

结论

与传统 FOAR 相比,治疗孤立性 UCS 的额眶牵引成骨术具有良好的围手术期发病率和较低的术后斜视发生率。但该技术还需要进行额外的移除装置手术,且缺乏长期的技术结果数据,这使上述优点受到影响。

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