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牵引成骨术与传统额眶前移术治疗单侧冠状缝早闭的比较:围手术期发病率及短期疗效对比

Distraction Osteogenesis Versus Conventional Fronto-Orbital Advancement for the Treatment of Unilateral Coronal Synostosis: A Comparison of Perioperative Morbidity and Short-Term Outcomes.

作者信息

Tahiri Youssef, Swanson Jordan W, Taylor Jesse A

机构信息

*Riley Hospital for Children, Indiana University, IN †Division of Plastic Surgery ‡Division of Plastic Surgery, The Perelman School of Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, PA.

出版信息

J Craniofac Surg. 2015 Sep;26(6):1904-8. doi: 10.1097/SCS.0000000000002020.

Abstract

Fronto-orbital advancement and remodeling (FOAR) remains the most widely practiced treatment of unicoronal craniosynostosis (UCS) despite recent studies of ocular dysfunction and aesthetic shortcomings in the long-term. The aim of the study was to compare perioperative morbidity and short-term outcomes of a recently developed, nondevascularizing, distraction-based treatment of UCS with conventional FOAR. To do so, the authors compared the first 6 patients who were treated with a new osteotomy/distraction approach to the last 6 patients who underwent traditional FOAR for the treatment of UCS with regards to demographics, operative details, perioperative morbidity, and short-term outcomes.Between July 2012 and June 2014, 6 patients underwent each procedure. Duration of surgery and length of hospital stay in the distraction group were on average 2 hours 7 minutes and 3.4 days, respectively, significantly less than in the traditional FOAR group (P = 0.039, P = 0.032, respectively). Perioperative blood loss averaged 169 mL, which trended toward less than in the traditional group (mean of 400 mL, P = 0.065). Patients undergoing conventional compared with distraction osteogenesis-mediated FOAR were significantly more likely to develop new-onset strabismus postoperatively (odds ratio 15.4; P = 0.0384). All 12 patients completed therapy without complications and with Whitaker grade I results at latest follow-up.In the perioperative period, distraction-mediated cranial vault remodeling provides similar correction of the aesthetic deformity associated with UCS and an improved morbidity profile. Longer follow-up is needed to determine how distraction compares with FOAR with respect to neuropsychologic and long-term aesthetic outcomes.

摘要

尽管近期有研究指出长期存在的眼功能障碍和美学缺陷,但额眶前移和重塑术(FOAR)仍是治疗单侧冠状缝早闭(UCS)最常用的方法。本研究旨在比较一种新开发的、非去血管化的、基于牵张的UCS治疗方法与传统FOAR的围手术期发病率和短期疗效。为此,作者比较了采用新截骨/牵张方法治疗的前6例患者和接受传统FOAR治疗UCS的后6例患者的人口统计学资料、手术细节、围手术期发病率和短期疗效。2012年7月至2014年6月,每组各有6例患者接受相应手术。牵张组的手术时间和住院时间平均分别为2小时7分钟和3.4天,显著短于传统FOAR组(分别为P = 0.039,P = 0.032)。围手术期平均失血量为169 mL,有低于传统组(平均400 mL)的趋势(P = 0.065)。与牵张成骨介导的FOAR相比,接受传统手术的患者术后新发斜视的可能性显著更高(优势比15.4;P = 0.0384)。所有12例患者均完成治疗,无并发症发生,最新随访时惠特克分级均为I级。在围手术期,牵张介导的颅盖重塑在矫正与UCS相关的美学畸形方面效果相似,且发病率更低。需要更长时间的随访来确定牵张术与FOAR在神经心理学和长期美学效果方面的差异。

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