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胸骨后甲状腺肿行甲状腺切除并胸骨切开术后发生气管软化——是虚构还是事实?

Tracheomalacia after thyroidectomy for retrosternal goitres requiring sternotomy- a myth or reality?

作者信息

Sulaiman A, Lutfi A, Ikram M, Fatimi S, Bin Pervez M, Shamim F, Abbas S A, Iftikhar H

机构信息

Aga Khan University Hospital, Karachi, Pakistan.

出版信息

Ann R Coll Surg Engl. 2021 Jul;103(7):504-507. doi: 10.1308/rcsann.2021.0014.

Abstract

INTRODUCTION

Tracheomalacia after thyroidectomy is not well understood. Reports on tracheomalacia are conflicting, with some suggesting a high rate and other large cohorts in which no tracheomalacia is reported. The aim of our study was to assess the incidence and factors associated with tracheomalacia after thyroidectomy in patients with retrosternal goitres requiring sternotomy at a high-volume tertiary care referral centre.

METHODS

A longitudinal cohort study was conducted from January 2011 to December 2019. All adult patients who underwent thyroidectomy with sternotomy were included. Tracheomalacia was considered when tracheal rings were soft compared with other parts (proximal or distal) of the trachea and required either tracheostomy or resection with anastomosis. The decision to perform a tracheostomy or to administer continuous or bilevel positive airway pressure postoperatively was made depending on the degree of tracheomalacia. Logistic regression analysis was used to assess factors associated with tracheomalacia.

RESULTS

We evaluated 40 patients who underwent thyroidectomy with sternotomy. The mean age of our cohort was 48.7 ± 11.3 years and the population was predominantly female (67.5%). One patient required tracheal resection with anastomosis, and two patients required tracheostomy. Multivariable logistic regression analysis did not reveal any patient- or thyroid-related factor significantly associated with the development of tracheomalacia in our cohort.

CONCLUSIONS

The incidence of tracheomalacia after thyroidectomy with sternotomy appears to be very low. However, the occurrence of tracheomalacia after thyroidectomy in cases of large goitre is possible and hence worrisome.

摘要

引言

甲状腺切除术后气管软化尚未得到充分了解。关于气管软化的报道相互矛盾,一些报道显示发生率较高,而其他大型队列研究则未报告有气管软化情况。我们研究的目的是评估在一家高容量三级医疗转诊中心,行胸骨切开术治疗胸骨后甲状腺肿的患者甲状腺切除术后气管软化的发生率及相关因素。

方法

2011年1月至2019年12月进行了一项纵向队列研究。纳入所有接受胸骨切开术的甲状腺切除术成年患者。当气管环与气管其他部位(近端或远端)相比变软,且需要气管造口术或切除吻合术时,考虑为气管软化。根据气管软化程度决定术后是否进行气管造口术或给予持续或双水平气道正压通气。采用逻辑回归分析评估与气管软化相关的因素。

结果

我们评估了40例行胸骨切开术的甲状腺切除术患者。我们队列的平均年龄为48.7±11.3岁,人群以女性为主(67.5%)。1例患者需要气管切除吻合术,2例患者需要气管造口术。多变量逻辑回归分析未发现我们队列中与气管软化发生显著相关的任何患者或甲状腺相关因素。

结论

胸骨切开术的甲状腺切除术后气管软化的发生率似乎非常低。然而,在巨大甲状腺肿病例中甲状腺切除术后发生气管软化是可能的,因此令人担忧。

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