Department of Lung Cancer Surgery, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cance, Tianjin, China (mainland).
Department of Thoracic Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China (mainland).
Med Sci Monit. 2022 Aug 11;28:e936637. doi: 10.12659/MSM.936637.
BACKGROUND Benign retrosternal thyroid goiters can become large enough to compress the trachea and result in tracheomalacia and stenosis. This retrospective study from a single surgical center aimed to study the surgical management of 48 patients with retrosternal goiter and tracheal stenosis diagnosed and treated from January 2017 to December 2021. MATERIAL AND METHODS All preoperative contrast-enhanced CT scans showed retrosternal goiter and tracheal stenosis. RG was classified into type I in 28 patients, type II in 12 patients, and type III in 8 patients. TS was classified into grade I in 31 patients, grade II in 11 patients, and grade III in 6 patients. All patients were referred for surgery. Clinicopathologic features and surgical outcomes were recorded. RESULTS All operations were successfully performed. There were 41 patients with transcervical incision, 4 with cervical incision+sternotomy, 2 with cervical incision and thoracoscopic surgery, and 1 with cervical incision and surgery via the subxiphoid approach. Two patients presented recurrent laryngeal nerve injury. One patient showed short-term hand and foot numbness. The patients were pathologically diagnosed as simple nodular goiter (n=27), nodular goiter combined with cystic change (n=6), adenomatous nodular goiter (n=10), and thyroid adenoma (n=5). There was no prominent tumor recurrence or gradual TS remission. CONCLUSIONS This study has highlighted that patients with retrosternal goiter and tracheal stenosis may have comorbidities and require a multidisciplinary approach to management. The choice of anesthesia, surgical approach, and maintenance of the airway during and after surgery should be individualized.
良性胸骨后甲状腺肿可长至足以压迫气管,导致气管软化和狭窄。本回顾性研究来自单一外科中心,旨在研究 2017 年 1 月至 2021 年 12 月期间诊断和治疗的 48 例胸骨后甲状腺肿和气管狭窄患者的外科治疗。
所有术前增强 CT 扫描均显示胸骨后甲状腺肿和气管狭窄。RG 分为 28 例Ⅰ型、12 例Ⅱ型和 8 例Ⅲ型;TS 分为 31 例Ⅰ级、11 例Ⅱ级和 6 例Ⅲ级。所有患者均接受手术治疗。记录临床病理特征和手术结果。
所有手术均成功完成。41 例经颈切口,4 例经颈切口+胸骨切开术,2 例经颈切口和胸腔镜手术,1 例经颈切口和剑突下手术。2 例出现喉返神经损伤,1 例出现短期手足麻木。患者病理诊断为单纯结节性甲状腺肿(n=27)、结节性甲状腺肿伴囊性变(n=6)、腺瘤样结节性甲状腺肿(n=10)和甲状腺腺瘤(n=5)。无明显肿瘤复发或 TS 逐渐缓解。
本研究强调,胸骨后甲状腺肿和气管狭窄患者可能存在合并症,需要多学科方法进行管理。麻醉、手术入路的选择以及手术期间和之后气道的维持应个体化。