Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Thorac Cancer. 2021 Aug;12(16):2241-2246. doi: 10.1111/1759-7714.14061. Epub 2021 Jun 30.
Data are lacking regarding pulmonary rehabilitation (PR) programs in patients with lung cancer receiving radiation therapy. This study aimed to confirm the feasibility of an outpatient-based PR program in lung cancer patients during radiation therapy.
A retrospective chart review was performed of 40 patients with lung cancer who had undergone radiation therapy between July and December 2019. The patients received an outpatient-based PR program for a total of eight sessions two times weekly comprising 60 min per session. Feasibility was assessed based on the completion rate, adverse events, and satisfaction with the PR program. Functional evaluations using 6-min walk and grip strength tests were conducted before and after PR. Patient quality of life was assessed by the EORTC QLQ-C30 questionnaire before and after PR.
The completion rate for the PR program was 72.5% among the 40 patients. No adverse events related to PR were reported. The overall satisfaction was 5.7 ± 1.1 on a seven-point Likert scale in all participants. The mean 6-min walk test distance increased significantly from 419.1 to 446.2 m. The improvement in grip strength in the dominant hand after PR was not significant. The social functioning score in the EORTC QLQ-C30 improved significantly.
The results of this study showed the feasibility without serious adverse effects of a 4-week outpatient-based PR program for lung cancer patients undergoing outpatient-based radiation therapy. This program might improve patient physical function and quality of life.
有关接受放射治疗的肺癌患者的肺康复(PR)计划的数据尚缺乏。本研究旨在确认在放射治疗期间为肺癌患者开展基于门诊的 PR 计划的可行性。
对 2019 年 7 月至 12 月期间接受放射治疗的 40 例肺癌患者进行了回顾性图表审查。这些患者共接受了 8 次基于门诊的 PR 计划,每周 2 次,每次 60 分钟。基于完成率、不良事件以及对 PR 计划的满意度来评估可行性。在 PR 前后进行 6 分钟步行和握力测试以进行功能评估。在 PR 前后通过 EORTC QLQ-C30 问卷评估患者的生活质量。
40 例患者中有 72.5%完成了 PR 计划。没有报告与 PR 相关的不良事件。所有参与者的整体满意度在七点李克特量表上得分为 5.7±1.1。6 分钟步行测试的平均距离从 419.1 米显著增加到 446.2 米。PR 后优势手握力的改善不显著。EORTC QLQ-C30 的社会功能评分显著提高。
本研究结果表明,对于接受门诊放射治疗的肺癌患者,开展为期 4 周的基于门诊的 PR 计划是可行的,且无严重不良事件。该计划可能改善患者的身体功能和生活质量。