Clinic of Neurosurgery, Sv Georgi University Hospital, Plovdiv, Bulgaria.
Department of Neurosurgery, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria.
Folia Med (Plovdiv). 2021 Jun 30;63(3):309-314. doi: 10.3897/folmed.63.e54750.
Tumours arising from the spinal nerve roots are more common in men between the third and fourth decades of life, located mainly in the intradural space of the lumbar region. The clinical symptoms of spinal schwannomas and neurofibromas are similar and depend on the location of the tumour and its relationship to the spinal cord and nerve roots. The pain (radiculalgia and/or vertebralgia) is the earliest symptom, followed by sensory deficit, while motor deficits and sphincter disorders are late symptoms. Magnetic resonance imaging is the diagnostic tool of choice and should be performed when the disease is suspected, as early and accurate diagnosis is essential for treatment outcome. The treatment of these lesions is surgical aiming at total tumour resection that promotes neurological recovery and prevents from recurrences. Subtotal removal also provides favourable outcome but at higher recurrence rates. The aim of this literature review was to study some important characteristics of sporadic spinal schwannomas (SSS) and neurofibromas (SSN), i.e. those notassociated with neurofibromatosis type I and II.
起源于脊神经根的肿瘤在 30 至 40 岁的男性中更为常见，主要位于腰椎的硬脊膜内。脊神经鞘瘤和神经纤维瘤的临床症状相似，取决于肿瘤的位置及其与脊髓和神经根的关系。疼痛（神经根痛和/或脊椎痛）是最早的症状，其次是感觉缺失，而运动缺陷和括约肌功能障碍是晚期症状。磁共振成像（MRI）是首选的诊断工具，应在怀疑患病时进行，因为早期和准确的诊断对治疗结果至关重要。这些病变的治疗方法是手术，旨在完全切除肿瘤，以促进神经恢复并防止复发。次全切除也能提供良好的结果，但复发率更高。本文献复习的目的是研究散发性脊神经鞘瘤（SSS）和神经纤维瘤（SSN）的一些重要特征，即不伴神经纤维瘤病 I 型和 II 型的脊神经鞘瘤和神经纤维瘤。
