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茎环查找器:一种用于检测具有保守基序的DNA发夹结构的工具。

StemLoop-Finder: a Tool for the Detection of DNA Hairpins with Conserved Motifs.

作者信息

Pratt Alyssa A, Torrance Ellis L, Kasun George W, Stedman Kenneth M, de la Higuera Ignacio

机构信息

Department of Biology, Center for Life in Extreme Environments, Portland State University, Portland, Oregon, USA.

Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon, USA.

出版信息

Microbiol Resour Announc. 2021 Jul;10(26):e0042421. doi: 10.1128/MRA.00424-21. Epub 2021 Jul 1.

DOI:10.1128/MRA.00424-21
PMID:34197205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8248882/
Abstract

Nucleic acid secondary structures play important roles in regulating biological processes. StemLoop-Finder is a computational tool to recognize and annotate conserved structural motifs in large data sets. The program is optimized for the detection of stem-loop structures that may serve as origins of replication in circular replication-associated protein (Rep)-encoding single-stranded (CRESS) DNA viruses.

摘要

核酸二级结构在调节生物过程中发挥着重要作用。茎环结构查找器是一种用于识别和注释大数据集中保守结构基序的计算工具。该程序经过优化,用于检测可能作为环状复制相关蛋白(Rep)编码单链(CRESS)DNA病毒复制起点的茎环结构。

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引用本文的文献

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本文引用的文献

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Unveiling Crucivirus Diversity by Mining Metagenomic Data.挖掘宏基因组数据揭示十字花科病毒多样性。
mBio. 2020 Sep 1;11(5):e01410-20. doi: 10.1128/mBio.01410-20.
2
: a Virus Phylum Unifying Seven Families of Rep-Encoding Viruses with Single-Stranded, Circular DNA Genomes.一个病毒门,统一了七个具有单链环状DNA基因组且编码复制相关蛋白的病毒科。
J Virol. 2020 Jun 1;94(12). doi: 10.1128/JVI.00582-20.
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Genome Sequences of Three Cruciviruses Found in the Willamette Valley (Oregon).在威拉米特河谷(俄勒冈州)发现的三种十字花科病毒的基因组序列。
Microbiol Resour Announc. 2019 Jun 6;8(23):e00447-19. doi: 10.1128/MRA.00447-19.
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Eukaryotic Circular Rep-Encoding Single-Stranded DNA (CRESS DNA) Viruses: Ubiquitous Viruses With Small Genomes and a Diverse Host Range.真核环状复制编码单链 DNA(CRESS DNA)病毒:具有小基因组和广泛宿主范围的普遍存在的病毒。
Adv Virus Res. 2019;103:71-133. doi: 10.1016/bs.aivir.2018.10.001. Epub 2018 Dec 5.
5
Virus discovery in all three major lineages of terrestrial arthropods highlights the diversity of single-stranded DNA viruses associated with invertebrates.在陆生节肢动物的所有三个主要谱系中发现病毒,凸显了与无脊椎动物相关的单链DNA病毒的多样性。
PeerJ. 2018 Oct 11;6:e5761. doi: 10.7717/peerj.5761. eCollection 2018.
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Diverse circular replication-associated protein encoding viruses circulating in invertebrates within a lake ecosystem.湖泊生态系统中无脊椎动物体内传播的多种编码环状复制相关蛋白的病毒。
Infect Genet Evol. 2016 Apr;39:304-316. doi: 10.1016/j.meegid.2016.02.011. Epub 2016 Feb 10.
7
Identification of several clades of novel single-stranded circular DNA viruses with conserved stem-loop structures in pig feces.在猪粪便中鉴定出几种具有保守茎环结构的新型单链环状DNA病毒进化枝。
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