1Department of Medicine and.
2Division of Neurosurgery, Department of Surgery, University of Toronto.
Neurosurg Focus. 2021 Jul;51(1):E3. doi: 10.3171/2021.4.FOCUS2198.
Mechanical endovascular thrombectomy (EVT) is an increasingly relied-on treatment for clot retrieval in the context of ischemic strokes, which otherwise are associated with significant morbidity and mortality. Despite several known risks associated with this procedure, there is a high degree of technical heterogeneity across both centers and operators. The most common procedural complications occur at the point of transfemoral access (the common femoral artery), and include access-site hematomas, dissections, and pseudoaneurysms. Other interventional fields have previously popularized the use of ultrasound to enhance the anatomical localization of structures relevant to vascular access and thereby reducing access-site complications. In this study, the authors aimed to describe the ultrasound-guided EVT technique performed at a large, quaternary neurovascular referral center, and to characterize the effects of ultrasound guidance on access-site complications.
A retrospective chart review of all patients treated with EVT at a single center between January 2013 and August 2020 was performed. Patients in this cohort were treated using a universal, unique, ultrasound-guided, single-wall puncture technique, which bears several theoretical advantages over the standard technique of arterial puncture via palpation.
There were 479 patients treated with EVT within the study period. Twenty patients in the cohort were identified as having experienced some form of access-site complication. Eight (1.67%) of these patients experienced minor access-site complications, all of which were groin hematomas and none of which were clinically significant, as defined by requiring surgical or interventional management or transfusion. The remaining 12 patients experienced arterial dissection (n = 5), arterial pseudoaneurysm (n = 4), retroperitoneal hematoma (n = 2), or arterial occlusion (n = 1), with only 1.04% (5/479) requiring surgical or interventional management or transfusion.
The authors found an overall reduction in total access-site complications as well as minor access-site complications in the study cohort compared with previously published randomized controlled trials and observational studies in the recent literature. The findings suggested that there may be a role for routine use of ultrasound-guided puncture techniques in EVT to decrease rates of complications.
机械血管内血栓切除术(EVT)是治疗缺血性中风时取栓的一种日益依赖的治疗方法,否则会导致严重的发病率和死亡率。尽管该手术存在几个已知的风险,但在中心和操作人员之间存在高度的技术异质性。最常见的手术并发症发生在经股入路(股总动脉)处,包括入路部位血肿、夹层和假性动脉瘤。其他介入领域之前已经推广了使用超声来增强与血管入路相关的结构的解剖定位,从而减少入路部位的并发症。在这项研究中,作者旨在描述在一个大型的四级神经血管转诊中心进行的超声引导 EVT 技术,并描述超声引导对入路部位并发症的影响。
对 2013 年 1 月至 2020 年 8 月期间在一家单一中心接受 EVT 治疗的所有患者进行了回顾性图表审查。该队列中的患者采用了一种通用的、独特的、超声引导的、单壁穿刺技术进行治疗,该技术与通过触诊进行动脉穿刺的标准技术相比具有若干理论优势。
在研究期间,有 479 名患者接受了 EVT 治疗。在队列中,有 20 名患者被确定发生了某种形式的入路部位并发症。其中 8 名(1.67%)患者出现轻微的入路部位并发症,均为腹股沟血肿,均无临床意义,即无需手术或介入治疗或输血。其余 12 名患者发生了动脉夹层(n=5)、动脉假性动脉瘤(n=4)、腹膜后血肿(n=2)或动脉闭塞(n=1),仅 1.04%(5/479)需要手术或介入治疗或输血。
与最近文献中的先前发表的随机对照试验和观察性研究相比,作者发现研究队列中的总入路部位并发症和轻微入路部位并发症均有所减少。这些发现表明,在 EVT 中常规使用超声引导穿刺技术可能会降低并发症的发生率。