Chen Wei-Tao, Teng Chin-Ann, Shih Cheng-Hsin, Huang Wei-Hsiang, Jiang Yi-Fan, Chang Hui-Wen, Jeng Chian-Ren, Lai Yen-Hsueh, Guo Jun-Cheng, Wang Pao-Jung, Cheng Chiu-Hung, Chang Yen-Chen
Graduate Institute of Molecular and Comparative Pathobiology, School of Veterinary Medicine, National Taiwan University, Taipei 10617, Taiwan.
Taipei Zoo, Taipei 116016, Taiwan.
Animals (Basel). 2021 Jun 2;11(6):1654. doi: 10.3390/ani11061654.
During the spring, an outbreak of sudden death involving 58 birds occurred in a zoo. Histopathological examinations revealed variable numbers of intracytoplasmic basophilic microorganisms in the macrophages, hepatocytes, and renal epithelium of most birds, along with occasional botryoid intracytoplasmic inclusion bodies within histiocytes in the bursa of Fabricius. Based on the results of histopathological examinations, immunohistochemical staining, transmission electron microscopy, and polymerase chain reactions, genotype B infection concurrent with pigeon circovirus (PiCV) was diagnosed. A retrospective survey, including two years before the outbreak and the outbreak year, of and PiCV infections of dead birds in the aviaries, revealed that the outbreak was an independent episode. The findings of this study indicate that concurrent infection with and PiCV might lead to lethal outbreaks of chlamydiosis, particularly In addition, persistently monitoring both pathogens and identifying potential PiCV carriers or transmitters might also help prevent lethal disease outbreaks.
春季期间，一家动物园发生了一起涉及58只鸟类的猝死疫情。组织病理学检查显示，大多数鸟类的巨噬细胞、肝细胞和肾上皮细胞内存在数量不等的胞质嗜碱性微生物，同时在法氏囊的组织细胞内偶尔可见葡萄状胞质内包涵体。根据组织病理学检查、免疫组织化学染色、透射电子显微镜检查和聚合酶链反应结果，诊断为基因型B感染并发鸽圆环病毒（PiCV）。对鸟舍中死鸟的鹦鹉热衣原体和PiCV感染进行的回顾性调查（包括疫情爆发前两年和爆发当年）显示，此次疫情是一次独立事件。本研究结果表明，鹦鹉热衣原体和PiCV的并发感染可能导致衣原体病的致死性疫情爆发，尤其是……此外，持续监测这两种病原体并识别潜在的PiCV携带者或传播者也可能有助于预防致死性疾病的爆发。
