Bacali Cecilia, Carpa Rahela, Buduru Smaranda, Moldovan Mirela L, Baldea Ioana, Constantin Annemarie, Moldovan Marioara, Prodan Doina, Dascalu Rusu Laura Monica, Lucaciu Ondine, Catoi Florinela, Constantiniuc Mariana, Badea Mandra
Department of Prosthodontics and Dental Materials, Iuliu Hatieganu University of Medicine and Pharmacy, Clinicilor 32, 400006 Cluj-Napoca, Romania.
Department of Molecular Biology and Biotechnology, Faculty of Biology and Geology, Babeș Bolyai University, 1 M. Kogălniceanu Street, 400084 Cluj-Napoca, Romania.
Nanomaterials (Basel). 2021 Jun 23;11(7):1643. doi: 10.3390/nano11071643.
(1) Background: Poor hygiene and denture presence in the oral cavity are factors that favor bacterial accumulation, the cause of halitosis and of various oral and general diseases. Aim: This study aimed to evaluate the possibility of inactivating bacteria associated with halitosis in acrylic denture wearers using polymethyl methacrylate resin enhanced with graphene silver nanoparticles and the effect of the resin association with extra oral photodynamic therapy. (2) Methods: Graphene silver nanoparticles in 1 and 2 wt% were added to a commercial acrylic resin powder. Three study groups containing samples from the three different materials were established. The first group was not exposed to the light treatment, and the other two were exposed to red light (laser and light emitting diode) after photosensitizer placement on the disk's surface. Samples were incubated with and . (3) Results: For both bacterial strains, inhibition zones were obtained, showing significant differences for the light-treated samples. (4) Conclusions: Denture resins with antibacterial properties associated with extra oral photodynamic therapy exhibited enhanced antibacterial effects. The procedure could be used as a safer and more efficient alternative technique against halitosis and oral infections in denture wearers.
(1) 背景：口腔卫生差和佩戴假牙是导致细菌积聚的因素，而细菌积聚是口臭以及各种口腔和全身性疾病的病因。目的：本研究旨在评估使用添加了石墨烯银纳米颗粒的聚甲基丙烯酸甲酯树脂使佩戴丙烯酸假牙者口腔中与口臭相关细菌失活的可能性，以及该树脂与口外光动力疗法联合使用的效果。(2) 方法：将1 wt%和2 wt%的石墨烯银纳米颗粒添加到商用丙烯酸树脂粉末中。建立了三个研究组，每组包含来自三种不同材料的样本。第一组未接受光处理，另外两组在将光敏剂置于圆盘表面后接受红光（激光和发光二极管）照射。样本与……一起培养。(3) 结果：对于两种细菌菌株，均获得了抑菌圈，光照处理后的样本显示出显著差异。(4) 结论：具有抗菌性能且与口外光动力疗法联合使用的假牙树脂表现出增强的抗菌效果。该方法可作为一种更安全、更有效的替代技术，用于治疗假牙佩戴者的口臭和口腔感染。
