Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.
Department of Otorhinolaryngology, Head and Neck Surgery, Taichung Hospital, Ministry of Health and Welfare, Taichung 403, Taiwan.
Int J Environ Res Public Health. 2021 Jun 24;18(13):6768. doi: 10.3390/ijerph18136768.
This article investigates the effects of continuous positive airway pressure (CPAP) on hearing impairment in sensorineural hearing loss (SNHL) patients with sleep-disordered breathing (SDB). This retrospective and observational study took place from September 2016 to February 2021, accumulating 77 subjects with SNHL and SDB (60.7 ± 11.1 years). Of which, 28 received CPAP treatment (63.0 ± 8.5 years). In our methodology, hearing thresholds at low, medium, high, and average frequencies are assessed by pure-tone audiometry at baseline (BL), three (3 m), six (6 m), and 12 (12 m) months. Our results show that the BL of at least three frequencies in all subjects is positively associated with old age, males, smoking, alcohol, coronary artery disease, hypertension, and apnea-hypopnea index [AHI] (all < 0.05). Moreover, low, medium, and average frequencies are negatively correlated at CPAP-6 m (-5.60 ± 2.33, -5.82 ± 2.56, and -5.10 ± 2.26 dB; all < 0.05) and CPAP-12 m (-7.97 ± 2.74, -8.15 ± 2.35, and -6.67 ± 2.37 dB; all < 0.01) against corresponding measures of CPAP-BL. High, medium, and average frequencies positively correlated with age ( < 0.001 for high and average frequencies and <0.01 for medium frequencies). We conclude that in SNHL patients with SDB, hearing thresholds at low and medium frequencies improves under CPAP use after six months, which persists at least to the end of one year.
本文研究了持续气道正压通气(CPAP)对伴有睡眠呼吸障碍(SDB)的感音神经性听力损失(SNHL)患者听力损伤的影响。这项回顾性观察研究于 2016 年 9 月至 2021 年 2 月进行,共纳入 77 例 SNHL 和 SDB 患者(60.7 ± 11.1 岁)。其中 28 例接受 CPAP 治疗(63.0 ± 8.5 岁)。在我们的方法中,通过纯音测听在基线(BL)、3 个月(3 m)、6 个月(6 m)和 12 个月(12 m)评估低频、中频、高频和平均频率的听力阈值。我们的结果表明,所有受试者的至少三个频率的 BL 与年龄较大、男性、吸烟、饮酒、冠状动脉疾病、高血压和呼吸暂停低通气指数 [AHI](均 < 0.05)呈正相关。此外,CPAP-6 m 时低频、中频和平均频率呈负相关(-5.60 ± 2.33、-5.82 ± 2.56 和-5.10 ± 2.26 dB;均 < 0.05),CPAP-12 m 时低频、中频和平均频率呈负相关(-7.97 ± 2.74、-8.15 ± 2.35 和-6.67 ± 2.37 dB;均 < 0.01),与 CPAP-BL 相应测量值呈负相关。高频、中频和平均频率与年龄呈正相关(高频和平均频率 < 0.001,中频 < 0.01)。我们得出结论,在伴有 SDB 的 SNHL 患者中,CPAP 使用 6 个月后低频和中频听力阈值改善,至少持续到一年结束。