Lin R C, Herman J, Henry L, Daniels G L
American Red Cross Blood Services, Penn-Jersey Region, Philadelphia, Pennsylvania.
Transfusion. 1988 Sep-Oct;28(5):427-9. doi: 10.1046/j.1537-2995.1988.28588337329.x.
An 86-year-old white American woman was found to have a very rare red cell phenotype, the Inab phenotype. Her cells were Cr(a-), Tc(a-b-c-), Dr(a-), Es(a-), WES(a-b-), and IFC-. Unlike the two other Inab phenotype patients, she has no history of protein-losing enteropathy or any similar intestinal disorder. One of her four siblings also has the Inab phenotype, providing the first evidence that this phenotype may be inherited. Serum inhibitions showed that anit-Cra, -TCa, -Dra, -WESb, and -IFC are partially inhibited by sera from three siblings with the common red cell phenotype but not by serum from the Inab phenotype sibling. The serum of the proposita contained an antibody to a high-frequency antigen that showed characteristics of being a Cromer-related antibody.
一名86岁的美国白人女性被发现具有一种非常罕见的红细胞表型,即Inab表型。她的细胞为Cr(a-)、Tc(a-b-c-)、Dr(a-)、Es(a-)、WES(a-b-)和IFC-。与另外两名Inab表型患者不同,她没有蛋白丢失性肠病或任何类似肠道疾病的病史。她的四个兄弟姐妹中有一人也具有Inab表型,这首次证明了该表型可能是可遗传的。血清抑制试验表明,抗Cra、-TCa、-Dra、-WESb和-IFC被三名具有常见红细胞表型的兄弟姐妹的血清部分抑制,但不被Inab表型兄弟姐妹的血清抑制。先证者的血清中含有一种针对高频抗原的抗体,该抗体表现出与克罗马相关抗体的特征。