Department of Radiology, Mayo Clinic College of Medicine and Science, Rochester, MN.
Division of Diagnostic Radiology, Washington University School of Medicine, St. Louis, Missouri.
J Vasc Interv Radiol. 2021 Jul;32(7):1089.e1-1089.e9. doi: 10.1016/j.jvir.2021.04.008.
Musculoskeletal interventions are increasingly used with palliative and curative intent in the multidisciplinary treatment of oncology patients with bone and soft-tissue tumors. There is an unmet need for high-quality evidence to guide broader application and adoption of minimally invasive interventional technologies to treat these patients. Therefore, the Society of Interventional Radiology Foundation and the Society of Interventional Oncology collaborated to convene a research consensus panel to prioritize a research agenda addressing the gaps in the current evidence. This article summarizes the panel's proceedings and recommendations for future basic science and clinical investigation to chart the course for interventional oncology within the musculoskeletal system. Key questions that emerged addressed the effectiveness of ablation within specific patient populations, the effect of combination of ablation with radiotherapy and/or immunotherapy, and the potential of standardization of techniques, including modeling and monitoring, to improve the consistency and predictability of treatment outcomes.
肌肉骨骼介入治疗越来越多地被用于肿瘤患者骨和软组织肿瘤的多学科治疗,具有姑息和治愈的目的。为了更广泛地应用和采用微创介入技术来治疗这些患者,高质量的证据是有需求的。因此,介入放射学基金会协会和介入肿瘤学协会合作,召集了一个研究共识小组,确定了一个研究议程,以解决当前证据中的空白。本文总结了小组的议事程序和对未来基础科学和临床研究的建议,为骨骼肌肉系统内的介入肿瘤学制定了路线图。出现的关键问题涉及到在特定患者群体中消融的有效性、消融与放疗和/或免疫疗法联合的效果,以及包括建模和监测在内的技术标准化的潜力,以提高治疗结果的一致性和可预测性。