Division of Interventional Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Division of Interventional Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Epidemiology and Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
J Vasc Interv Radiol. 2021 Sep;32(9):1388.e1-1388.e14. doi: 10.1016/j.jvir.2021.05.029.
The Society of Interventional Radiology Foundation commissioned a Research Consensus Panel to establish a research agenda on "Obesity Therapeutics" in interventional radiology (IR). The meeting convened a multidisciplinary group of physicians and scientists with expertise in obesity therapeutics. The meeting was intended to review current evidence on obesity therapies, familiarize attendees with the regulatory evaluation process, and identify research deficiencies in IR bariatric interventions, with the goal of prioritizing future high-quality research that would move the field forward. The panelists agreed that a weight loss of >8%-10% from baseline at 6-12 months is a desirable therapeutic endpoint for future IR weight loss therapies. The final consensus on the highest priority research was to design a blinded randomized controlled trial of IR weight loss interventions versus sham control arms, with patients receiving behavioral therapy.
介入放射学基金会委托一个研究共识小组制定介入放射学(IR)领域的“肥胖治疗”研究议程。会议召集了一组具有肥胖治疗专业知识的多学科医生和科学家。会议旨在审查肥胖治疗的现有证据,使与会者熟悉监管评估过程,并确定肥胖症治疗的研究缺陷,目的是确定未来能够推动该领域发展的高质量研究的优先事项。小组成员一致认为,在 6-12 个月时,与基线相比体重减轻 >8%-10%是未来 IR 减肥治疗的理想治疗终点。关于最高优先级研究的最终共识是设计一项针对 IR 减肥干预与假对照臂的盲法随机对照试验,让患者接受行为疗法。