三叉神经痛导致卵巢癌的诊断：是及时的巧合还是副肿瘤综合征的病例？
Trigeminal neuralgia leading to a diagnosis of ovarian cancer: a timely coincidence or a case of paraneoplastic syndrome?
机构信息
Gynaecology, Guy's and St Thomas' Hospitals NHS Trust, London, UK
Faculty of Life Sciences and Medicine, King's College London, London, UK.
出版信息
BMJ Case Rep. 2021 Jul 1;14(7):e243480. doi: 10.1136/bcr-2021-243480.
Abstract
A 51-year-old woman was referred to oral medicine with a 2-month history of progressive paraesthesia of the right lip, chin and oral mucosa. Examination revealed decreased sensation to the right dermatone of the inferior alveolar nerve and allodynia to light touch of the lower lip. An MRI of the head revealed bilateral cisternal trigeminal nerve pathological enhancement. While blood tests suggested a connective tissue disorder as the cause of the trigeminal neuralgia, a subsequent diagnosis of high-grade serous ovarian cancer gave a differential diagnosis of paraneoplastic syndrome.
摘要
一位 51 岁女性因右侧唇、颏和口腔黏膜进行性感觉异常，被转至口腔医学科就诊。检查发现，下牙槽神经的右侧皮节感觉减退，下唇轻触时有感觉过敏。头部 MRI 显示双侧桥脑池三叉神经病理性增强。尽管血液检查提示结缔组织疾病是导致三叉神经痛的原因，但随后诊断出高级别浆液性卵巢癌，提示副肿瘤综合征的鉴别诊断。
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