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减重手术后特发性硬膜外脂肪增多症的消退:病例报告及文献综述

Resolution of Idiopathic Epidural Lipomatosis after Bariatric Surgery: Case Report and Literature Review.

作者信息

Alsofyani Mohammad A, Alsalmi Sultan, Malaekah Haifaa, Alharthi Majed, Bourghli Anouar, Obeid Ibrahim, Boissière Louis

机构信息

Department of Surgery, College of Medicine and University Hospital, University of Hail, Hail, Kingdom of Saudi Arabia.

Department of Neurosurgery, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.

出版信息

Asian J Neurosurg. 2021 Feb 23;16(1):217-220. doi: 10.4103/ajns.AJNS_294_20. eCollection 2021 Jan-Mar.

DOI:10.4103/ajns.AJNS_294_20
PMID:34211899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8202365/
Abstract

Spinal epidural lipomatosis (SEL) is traditionally a rare disorder defined as an abnormal accumulation of unencapsulated epidural fat. SEL can be classified into idiopathic and secondary. We report a 46-year-old obese male with idiopathic epidural lipomatosis with a clinical picture of bilateral L5 and S1 radiculopathy, with an L5 and S1 distribution. Magnetic resonance imaging (MRI) showed epidural lipomatosis at L4, L5, and S1. After 2-year of sleeve gastrectomy, his bilateral sciatic radiculopathy disappeared, and updated MRI showed complete resolution of epidural lipomatosis. We present a case of an unusual epidural lipomatosis, resolved completely by bariatric surgery. This case report set out the effect of metabolic surgery on the local and systemic metabolic process.

摘要

脊髓硬膜外脂肪增多症(SEL)传统上是一种罕见疾病,定义为未包裹的硬膜外脂肪异常蓄积。SEL可分为特发性和继发性。我们报告一例46岁肥胖男性特发性硬膜外脂肪增多症,临床表现为双侧L5和S1神经根病,呈L5和S1分布。磁共振成像(MRI)显示L4、L5和S1水平硬膜外脂肪增多。在接受袖状胃切除术后2年,其双侧坐骨神经神经根病消失,复查MRI显示硬膜外脂肪增多症完全消退。我们呈现一例罕见的硬膜外脂肪增多症病例,通过减重手术完全治愈。本病例报告阐述了代谢手术对局部和全身代谢过程的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7439/8202365/d4c955d52ff0/AJNS-16-217-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7439/8202365/faa875212d95/AJNS-16-217-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7439/8202365/d4c955d52ff0/AJNS-16-217-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7439/8202365/faa875212d95/AJNS-16-217-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7439/8202365/d4c955d52ff0/AJNS-16-217-g002.jpg

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本文引用的文献

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2
Metabolic and Endocrine Consequences of Bariatric Surgery.减肥手术的代谢和内分泌后果。
Front Endocrinol (Lausanne). 2019 Sep 19;10:626. doi: 10.3389/fendo.2019.00626. eCollection 2019.
3
Epidural Lipomatosis and Associated Spinal Stenosis-The Impact of Weight Loss: A Case Report.
硬膜外脂肪增多症及相关的椎管狭窄——体重减轻的影响:一例报告
Am J Lifestyle Med. 2017 Jan 12;11(6):511-514. doi: 10.1177/1559827616686764. eCollection 2017 Nov-Dec.
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The role of adipose tissue and excess of fatty acids in the induction of insulin resistance in skeletal muscle.脂肪组织和脂肪酸过量在骨骼肌胰岛素抵抗诱导中的作用。
Postepy Hig Med Dosw (Online). 2016 Nov 14;70(0):1142-1149. doi: 10.5604/17322693.1224257.
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