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墨西哥城一家三级医院确诊 COVID-19 儿科患者的临床和流行病学特征。

Clinical and Epidemiological Characteristics of Paediatric Patients Diagnosed with COVID-19 in a Tertiary Hospital in Mexico City.

机构信息

Medical Director, Instituto Nacional de Pediatría, National Pediatrics Institute, Insurgentes Cuicuilco, Coyoacán, Mexico City, CP 04530, Mexico.

Pediatric Infectious Disease Department, National Pediatrics Institute, Mexico City, Mexico.

出版信息

J Trop Pediatr. 2021 Jul 2;67(3). doi: 10.1093/tropej/fmab025.

Abstract

COVID-19 affects the paediatric population less frequently than adults. A retrospective study was performed in a tertiary paediatric hospital in Mexico City in children <18 years of age who were hospitalized with a positive reverse transcription-polymerase chain reaction for SARS-CoV-2. Included in the study were 86 patients with a median age of 10 years old (IQR 2.6-14.3 years), who were classified in three groups: previously healthy, with chronic disease and immunosuppressed patients. The principal signs and symptoms were fever (81%), cough (51%) and headache (35%). A total of 20 patients (23%) required management in the paediatric intensive care unit (PICU) and 17% needed mechanical ventilation for an average of 12.7 days (IQR 2-29 days). There was no statistically significant difference between the three clinical classification groups in those patients admitted to the PICU, most of which were previously healthy patients. The mortality rate was 5% (four patients). Given that the paediatric population is susceptible to infection, potential transmitters and to clinical presentations with variable degrees of severity, it is important to continue reinforcing social distancing measures.

摘要

COVID-19 在儿童中的影响不如成年人频繁。在墨西哥城的一家三级儿科医院进行了一项回顾性研究,纳入了因 SARS-CoV-2 逆转录-聚合酶链反应阳性而住院的<18 岁儿童。研究包括 86 例中位年龄为 10 岁(IQR 2.6-14.3 岁)的患者,他们分为三组:健康、患有慢性疾病和免疫抑制的患者。主要的体征和症状是发热(81%)、咳嗽(51%)和头痛(35%)。共有 20 名患者(23%)需要在儿科重症监护病房(PICU)治疗,17%需要机械通气,平均 12.7 天(IQR 2-29 天)。在需要入住 PICU 的患者中,三组临床分类组之间无统计学差异,其中大多数是健康的患者。死亡率为 5%(4 例)。鉴于儿童易感染、潜在的传播者以及表现出不同严重程度的临床表现,继续加强社会隔离措施非常重要。

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