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西纳罗亚州儿童感染 SARS-CoV-2 的临床和流行病学特征:病例系列研究

Clinical and epidemiological characteristics of children with SARS-CoV-2 infection: a case series in Sinaloa.

机构信息

Hospital Pediátrico de Sinaloa Dr. Rigoberto Aguilar Pico, Servicios de Salud de Sinaloa. Culiacán, Sinaloa, Mexico.

Unidad de Inteligencia Epidemiológica, Servicios de Salud de Sinaloa. Culiacán, Sinaloa, Mexico.

出版信息

Bol Med Hosp Infant Mex. 2021;78(1):18-23. doi: 10.24875/BMHIM.200002021.

DOI:10.24875/BMHIM.200002021
PMID:33661874
Abstract

BACKGROUND

The SARS-CoV-2 virus may affect both adults and children. Although COVID-19 has a lower prevalence in infancy and has been described as mild, the clinical characteristics may vary, and there is a possibility of complications. The objectives of this study were to describe the clinical and epidemiological aspects of confirmed COVID-19 pediatric cases in the state of Sinaloa, Mexico, during the first 3 months of the pandemic, and children admitted with COVID-19 to a secondary hospital.

METHODS

This case series includes all patients with SARS-CoV-2 infection confirmed by PCR (polymerase chain reaction) test, identified in the state epidemiological surveillance system (SISVER) between March 1 and May 31, 2020. Confirmed patients admitted to the Sinaloa Pediatric Hospital (HPS) in the same period are also described.

RESULTS

Fifty-one children with SARS-CoV-2 were included, of which ten were admitted to the HPS. The median age was 10 years. The more frequent symptoms were fever (78%), cough (67%), and headache (57%). Most cases were mild or asymptomatic. Three patients with comorbidities died. Only four of ten patients identified in HPS were admitted with the diagnosis of possible COVID-19.

CONCLUSIONS

SARS-CoV-2 infection in children was mostly mild or asymptomatic, and the clinical presentation varied. There is a possibility of complications, especially in children with comorbidities.

摘要

背景

SARS-CoV-2 病毒可能会影响到成人和儿童。虽然 COVID-19 在婴儿中发病率较低,且被描述为轻症,但临床表现可能会有所不同,并且存在出现并发症的可能。本研究的目的是描述墨西哥锡那罗亚州在大流行的前 3 个月中经聚合酶链反应(PCR)检测确诊的 COVID-19 儿科病例以及因 COVID-19 住院的二级医院儿童患者的临床和流行病学特征。

方法

本病例系列研究纳入了 2020 年 3 月 1 日至 5 月 31 日期间通过州流行病学监测系统(SISVER)识别的所有经 PCR 检测确诊的 SARS-CoV-2 感染患者。还描述了同期在锡那罗亚儿科医院(HPS)住院的确诊患者。

结果

共纳入了 51 例 SARS-CoV-2 患儿,其中 10 例患儿收入 HPS。中位年龄为 10 岁。更常见的症状是发热(78%)、咳嗽(67%)和头痛(57%)。大多数病例为轻症或无症状。3 例合并症患者死亡。在 HPS 中发现的 10 例患者中,仅有 4 例是以可能的 COVID-19 为诊断而收入院的。

结论

儿童 SARS-CoV-2 感染多为轻症或无症状,临床表现各异。特别是合并症儿童存在发生并发症的可能。

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