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认证癌症中心提供的治疗是否更具成本效益?利用行政数据对德国结肠癌治疗进行的卫生经济分析。

Do certified cancer centers provide more cost-effective care? A health economic analysis of colon cancer care in Germany using administrative data.

机构信息

Division of Health Economics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.

出版信息

Int J Cancer. 2021 Nov 15;149(10):1744-1754. doi: 10.1002/ijc.33728. Epub 2021 Jul 27.

Abstract

Hospital certification has become an important measure to improve cancer care quality, with the potential effect of prolonging patient survival and reducing medical spending. However, yet to be explored is the cost-effectiveness of cancer care provided in certified hospitals, considering significant additional costs incurred from certification requirements. We performed a cost-effectiveness analysis (CEA) using two colon cancer populations (N = 1909) treated in different levels of certified hospitals (CHs) vs noncertified hospitals (NCHs) from a healthcare system's perspective. We matched patient-level data of incident colon cancer cases, diagnosed between 2008 and 2013 from a large statutory health insurance in Saxony, Germany, to calculate net treatment costs by phase (initial, continuing and terminal phase). The costs were supplemented with extra costs from 31 additional services required for certification. Effectiveness measure was total survival time in life-years. Outcome of interest was incremental costs per additional life-year. The annualized net colon cancer treatment costs by phase showed a U shape with high costs in the initial (mean €26 855; 95% CI €25 058-€28 652) and the terminal phases (mean €30 096; 95% CI €26 199-€33 993). The base-case CEA results and all sensitivity analyses consistently demonstrated longer survival and lower costs for the colon cancer cohort treated in CHs vs NCHs. To conclude, we used administrative data to derive the first cost-effectiveness evidence supporting that colon cancer care delivered in the certified cancer centers in Germany improves survival outcomes and saves costs from a healthcare system's perspective. Generalization of the study results should be exercised with caution.

摘要

医院认证已成为提高癌症护理质量的重要手段,可能具有延长患者生存时间和降低医疗支出的效果。然而,考虑到认证要求带来的显著额外成本,认证医院提供的癌症护理的成本效益尚未得到探索。我们从医疗保健系统的角度,使用两种不同级别认证医院(CH)和非认证医院(NCH)治疗的两种结肠癌患者群体(N=1909)进行了成本效益分析(CEA)。我们匹配了德国萨克森州一家大型法定健康保险中 2008 年至 2013 年间确诊的结肠癌病例的患者水平数据,以按阶段(初始阶段、持续阶段和终末阶段)计算净治疗成本。该成本补充了 31 项额外认证服务所需的额外成本。有效性测量指标为总生存时间(以生命年计)。关注的结果是每额外增加一个生命年的增量成本。各阶段的年化净结肠癌治疗成本呈 U 形,初始阶段(平均 26855 欧元;95%置信区间 25058 欧元至 28652 欧元)和终末阶段(平均 30096 欧元;95%置信区间 26199 欧元至 33993 欧元)成本较高。基本情况 CEA 结果和所有敏感性分析均一致表明,CH 治疗的结肠癌患者队列的生存时间更长,成本更低。总之,我们使用行政数据首次得出了支持德国认证癌症中心提供的结肠癌护理可改善生存结果并从医疗保健系统角度节省成本的成本效益证据。应谨慎推广研究结果。

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