Université Grenoble Alpes, CNRS, CEA, INRAe, IRIG-LPCV, UMR5168, 38000 Grenoble, France.
Université Grenoble Alpes, Inserm, CEA, IRIG-BGE, U1038, 38000, Grenoble, France.
C R Biol. 2021 Jul 2;344(2):157-163. doi: 10.5802/crbiol.49.
Can we understand how plant cell metabolism really works? An integrated large-scale modelling of plant metabolism predictive model would make possible to analyse the impact of disturbances in environmental conditions on cellular functioning and diversity of plant-made molecules of interest. ChloroKB, a Web application initially developed for exploration of Arabidopsis chloroplast metabolic network now covers Arabidopsis mesophyll cell metabolism. Interconnected metabolic maps show subcellular compartments, metabolites, proteins, complexes, reactions, and transport. Data in ChloroKB have been structured to allow for mathematical modelling and will be used as a reference for modelling work dedicated to a particular issue.
我们能否真正理解植物细胞代谢的运作方式？对植物代谢进行综合的大规模建模预测，将有可能分析环境条件的干扰对细胞功能和感兴趣的植物制造分子多样性的影响。ChloroKB 最初是为探索拟南芥叶绿体代谢网络而开发的一个网络应用程序，现在涵盖了拟南芥叶肉细胞的代谢。相互连接的代谢图显示了亚细胞区室、代谢物、蛋白质、复合物、反应和运输。ChloroKB 中的数据经过了结构化处理，以便进行数学建模，并将作为专门针对特定问题的建模工作的参考。
