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TomoTherapy、CyberKnife 和无均整滤过线性加速器输出测量的放射光致发光玻璃剂量计的剂量响应在剂量学审核中的研究。

Dose response of a radiophotoluminescent glass dosimeter for TomoTherapy, CyberKnife, and flattening-filter-free linear accelerator output measurements in dosimetry audit.

机构信息

QST Hospital, National Institutes for Quantum and Radiological Science and Technology, Japan.

Association for Nuclear Technology in Medicine, Japan.

出版信息

Phys Med. 2021 Aug;88:91-97. doi: 10.1016/j.ejmp.2021.06.010. Epub 2021 Jun 29.

Abstract

PURPOSE

We experimentally determined the radiophotoluminescent glass dosimeter (RPLD) dose responses for TomoTherapy, CyberKnife, and flattening-filter-free (FFF) linear accelerator (linac) outputs for dosimetry audits in Japan.

METHODS

A custom-made solid phantom with a narrow central-axis spacing of three RPLD elements was used for output measurement to minimise the dose-gradient effect of the non-flattening filter beams. For RPLD dose estimation, we used the ISO 22127 formalism. Additional unit-specific correction factors were introduced and determined via the measured data. For TomoTherapy (7 units) and CyberKnife (4 units), the doses were measured under machine-specific reference fields. For FFF linac (5 units), in addition to the reference condition, we obtained the field-size effects for the range from 5×5 cm to 25×25 cm.

RESULTS

The correction factors were estimated as 1.008 and 0.999 for TomoTherapy and CyberKnife, respectively. For FFF linac, they ranged from 1.011 to 0.988 for 6 MV and from 1.011 to 0.997 for 10 MV as a function of the side length of the square field from 5 to 25 cm. The estimated uncertainties of the absorbed dose to water measured by RPLD for the units were 1.32%, 1.35%, and 1.30% for TomoTherapy, CyberKnife, and FFF linac, respectively. A summary of the dosimetry audits of these treatment units using the obtained correction factors is also presented. The average percentage differences between the measured and hospital-stated doses were <1% under all conditions.

CONCLUSION

RPLD can be successfully used as a dosimetry audit tool for modern treatment units.

摘要

目的

我们通过实验确定了放射光致发光玻璃剂量计(RPLD)在日本剂量审计中的 TomoTherapy、CyberKnife 和无均整滤过(FFF)直线加速器(linac)输出的剂量响应。

方法

使用带有三个 RPLD 元件的窄中心轴间距的定制固体体模进行输出测量,以最小化非均整滤过束的剂量梯度效应。对于 RPLD 剂量估计,我们使用了 ISO 22127 形式。通过测量数据引入并确定了额外的单位特定校正因子。对于 TomoTherapy(7 个单位)和 CyberKnife(4 个单位),在机器特定参考场下测量剂量。对于 FFF linac(5 个单位),除了参考条件外,我们还获得了 5×5 cm 至 25×25 cm 范围内的射野尺寸效应。

结果

校正因子分别估计为 TomoTherapy 和 CyberKnife 的 1.008 和 0.999。对于 FFF linac,6 MV 的校正因子范围为 1.011 至 0.988,10 MV 的校正因子范围为 1.011 至 0.997,作为正方形射野边长从 5 至 25 cm 的函数。用 RPLD 测量的水吸收剂量的不确定度分别为 TomoTherapy、CyberKnife 和 FFF linac 的 1.32%、1.35%和 1.30%。还介绍了使用获得的校正因子对这些治疗单元进行剂量审计的总结。在所有条件下,测量剂量与医院报告剂量的平均百分比差异均<1%。

结论

RPLD 可以成功用作现代治疗单元的剂量审计工具。

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