HacettepeUniversity Hospitals, Neurology Department, Neurocritical Care and Stroke Units, Ankara, Turkey.
Hacettepe University Hospitals, Radiology Department, Ankara, Turkey.
Clin Neurol Neurosurg. 2021 Aug;207:106779. doi: 10.1016/j.clineuro.2021.106779. Epub 2021 Jun 24.
We studied the proposal to modify the ABC/2 formula to ABC/3 for irregular-shaped intracerebral hematoma (ICH) volume estimation.
The volume of 133 ICHs were estimated with Kwak's (simplified C; all slices with hemorrhage are considered equal), Kothari's (weighted C) and coronal (reformatted C; measuring C directly on coronal reformatted images) ABC/2 methods, and compared with computer-assisted planimetric measurements. The accuracy, precision and correlation of three ABC/2 methods and their ABC/3 modifications were determined in smooth (Barras' group 1 or 2) and irregular (Barras' group 3-5) shaped ICHs.
As the hematoma size increases, the shape becomes irregular. In all hematomas, both smooth (n = 81) and irregular (n = 52) shaped, Kothari's ABC/2 formula provided the closest result to the planimetric measurement, with an underestimation of 1.77 mL, and 10.2% difference on average. Kothari's ABC/2 disclosed the best correlation (Lin's coefficient=0.9622) regardless of ICH shape. When simplified-ABC/2 method was modified as ABC/3, volume estimation accuracy increased (Correlation coefficient increased from 0.838 to 0.915) for irregular hematomas; however, despite this improvement the accuracy remained below the Kothari's ABC/2 (not ABC/3) method. Neither reformatted coronal ABC/2 nor its ABC/3 modification provided any advantage over ABC/x formulas with slice counting.
Kothari's ABC/2 method is a valid method for estimation of ICH volume for both regular and irregular shaped hematomas. Simplified (Kwak's) ABC/2 or coronal ABC/2, or their /3 counterparts do not provide additional advantage.
我们研究了修改 ABC/2 公式为 ABC/3 以估计不规则形状脑内血肿（ICH）体积的建议。
使用 Kwak 的简化 C（所有血肿切片均视为相等）、Kothari 的加权 C 和冠状面（直接在冠状面重建图像上测量 C）ABC/2 方法估计 133 例 ICH 体积，并与计算机辅助平面测量进行比较。确定三种 ABC/2 方法及其 ABC/3 修正在规则（Barras 组 1 或 2）和不规则（Barras 组 3-5）形状 ICH 中的准确性、精度和相关性。
随着血肿大小的增加，形状变得不规则。在所有血肿中，无论是规则形状（n=81）还是不规则形状（n=52），Kothari 的 ABC/2 公式提供了与平面测量最接近的结果，低估了 1.77 mL，平均差异为 10.2%。Kothari 的 ABC/2 无论 ICH 形状如何，均显示出最佳相关性（Lin 系数=0.9622）。当简化 ABC/2 方法被修改为 ABC/3 时，不规则血肿的体积估计准确性提高（相关系数从 0.838 增加到 0.915）；然而，尽管有这种改进，其准确性仍然低于 Kothari 的 ABC/2（而非 ABC/3）方法。冠状面 ABC/2 或其 ABC/3 修正均未优于基于切片计数的 ABC/x 公式。
Kothari 的 ABC/2 方法是用于估计规则和不规则形状 ICH 体积的有效方法。简化（Kwak 的）ABC/2 或冠状面 ABC/2 或其 ABC/3 对应物没有提供额外的优势。
