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Endometriosis of para-aortic node masquerading a malignancy: a rare occurrence.腹主动脉旁淋巴结子宫内膜异位症伪装恶性肿瘤：罕见发生。
BMJ Case Rep. 2021 Jul 2;14(7):e240750. doi: 10.1136/bcr-2020-240750.
2
Endometriosis in para-aortic lymph node resembling a malignancy: a case report and literature review.腹膜后淋巴结子宫内膜异位症类似于恶性肿瘤：病例报告及文献复习。
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3
Lymphovascular space invasion and positive pelvic lymph nodes are independent risk factors for para-aortic nodal metastasis in endometrioid endometrial cancer.淋巴管间隙浸润和盆腔淋巴结阳性是子宫内膜样子宫内膜癌腹主动脉旁淋巴结转移的独立危险因素。
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4
Endometriosis in para-aortic lymph nodes during pregnancy: case report and review of literature.妊娠时腹主动脉旁淋巴结子宫内膜异位症：病例报告及文献复习。
Fertil Steril. 2011 Jun;95(7):2429.e9-13. doi: 10.1016/j.fertnstert.2011.01.157. Epub 2011 Feb 26.
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Int J Gynecol Cancer. 2006 Mar-Apr;16(2):799-804. doi: 10.1111/j.1525-1438.2006.00529.x.
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The role of the lymphatic system in endometriosis: a comprehensive review of the literature.淋巴系统在子宫内膜异位症中的作用：文献综述
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[Clinical analysis on the lymph nodes metastasis characters and their relation with the prognosis of the endometrial carcinoma patients].[子宫内膜癌患者淋巴结转移特征及其与预后关系的临床分析]
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A retrospective analysis of the diameter of metastatic lymph nodes in apparently early stage endometrial cancer.早期子宫内膜癌转移性淋巴结直径的回顾性分析
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Ultrastaging of para-aortic lymph nodes in stage IIIC1 endometrial cancer: a preliminary report.盆腔淋巴结分期在 IIIC1 期子宫内膜癌中的应用：初步报告。
Gynecol Oncol. 2012 Dec;127(3):532-7. doi: 10.1016/j.ygyno.2012.08.026. Epub 2012 Aug 30.

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The role of TGF-β superfamily in endometriosis: a systematic review.转化生长因子-β超家族在子宫内膜异位症中的作用：一项系统评价
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A Case of Rectal Endometriosis Misdiagnosed as Rectal Malignancy on Three Colonoscopies and Biopsies Sharing a Combined Literature Review.一例经三次结肠镜检查及活检均误诊为直肠恶性肿瘤的直肠子宫内膜异位症病例并附文献综述
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Endometriosis in para-aortic lymph node resembling a malignancy: a case report and literature review.腹膜后淋巴结子宫内膜异位症类似于恶性肿瘤：病例报告及文献复习。
BMC Womens Health. 2022 Apr 5;22(1):101. doi: 10.1186/s12905-022-01659-4.

本文引用的文献

1
Endometriosis-associated ovarian carcinomas: insights into pathogenesis, diagnostics, and therapeutic targets-a narrative review.子宫内膜异位症相关卵巢癌：发病机制、诊断及治疗靶点的见解——一篇叙述性综述
Ann Transl Med. 2020 Dec;8(24):1712. doi: 10.21037/atm-20-3022a.
2
Wise Management of Ovarian Cancer: On the Cutting Edge.卵巢癌的明智管理：处于前沿领域
J Pers Med. 2020 May 21;10(2):41. doi: 10.3390/jpm10020041.
3
Deep Quantitative Proteomics Reveals Extensive Metabolic Reprogramming and Cancer-Like Changes of Ectopic Endometriotic Stromal Cells.深度定量蛋白质组学揭示异位子宫内膜间质细胞广泛的代谢重编程和类癌变化。
J Proteome Res. 2016 Feb 5;15(2):572-84. doi: 10.1021/acs.jproteome.5b00965. Epub 2015 Dec 23.
4
The role of the lymphatic system in endometriosis: a comprehensive review of the literature.淋巴系统在子宫内膜异位症中的作用：文献综述
Biol Reprod. 2015 Mar;92(3):64. doi: 10.1095/biolreprod.114.124313. Epub 2015 Jan 14.
5
Lymphatic spread of endometriosis to para-aortic nodes.子宫内膜异位症向主动脉旁淋巴结的淋巴扩散。
J Minim Invasive Gynecol. 2013 Nov-Dec;20(6):741. doi: 10.1016/j.jmig.2013.02.014.
6
Lymphatic spread of endometriosis to pelvic sentinel lymph nodes: a prospective clinical study.子宫内膜异位症向盆腔前哨淋巴结的淋巴转移：一项前瞻性临床研究。
Fertil Steril. 2011 Sep;96(3):692-6. doi: 10.1016/j.fertnstert.2011.06.070.
7
Relationship between endometriosis and cancer from current perspective.从当前视角看子宫内膜异位症与癌症的关系。
Arch Gynecol Obstet. 2011 Dec;284(6):1473-9. doi: 10.1007/s00404-011-2047-y. Epub 2011 Aug 12.
8
The association between endometriosis and gynecological cancers and breast cancer: a review of epidemiological data.子宫内膜异位症与妇科癌症和乳腺癌的关联：流行病学数据综述。
Gynecol Oncol. 2011 Oct;123(1):157-63. doi: 10.1016/j.ygyno.2011.06.017. Epub 2011 Jul 13.
9
Endometriosis in para-aortic lymph nodes during pregnancy: case report and review of literature.妊娠时腹主动脉旁淋巴结子宫内膜异位症：病例报告及文献复习。
Fertil Steril. 2011 Jun;95(7):2429.e9-13. doi: 10.1016/j.fertnstert.2011.01.157. Epub 2011 Feb 26.
10
Pathogenesis of endometriosis based on endometrial homeoplasia, direct extension, exfoliation and implantation, lymphatic and hematogenous metastasis, including five case reports of endometrial tissue in pelvic lymph nodes.基于子宫内膜化生、直接蔓延、脱落与种植、淋巴及血行转移的子宫内膜异位症发病机制，包括盆腔淋巴结内子宫内膜组织的5例报告
Cancer. 1949 May;2(3):399-410. doi: 10.1002/1097-0142(194905)2:3<399::aid-cncr2820020304>3.0.co;2-l.

腹主动脉旁淋巴结子宫内膜异位症伪装恶性肿瘤：罕见发生。

Endometriosis of para-aortic node masquerading a malignancy: a rare occurrence.

机构信息

Obstetrics and Gynecology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamilnadu, India

Department of Surgical Oncology, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India.

出版信息

BMJ Case Rep. 2021 Jul 2;14(7):e240750. doi: 10.1136/bcr-2020-240750.

DOI:10.1136/bcr-2020-240750
PMID:34215635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8256722/
Abstract

Endometriosis is a benign estrogen-dependent disorder affecting women in their reproductive age group. Endometriosis means 'abnormal growth of endometrial glands' outside the uterus. Multiple theories on aetiopathogenesis of endometriosis have been postulated, Halban's theory on 'Benign Metastasis' which proposed the presence of endometriotic cells in lymphatic vessels and lymph nodes provides the basis of this case report. Here, we report a case of 26-year-old nulliparous woman who presented with grossly elevated CA 125 with endometriosis in her para-aortic nodes mimicking as ovarian cancer.

摘要

子宫内膜异位症是一种良性雌激素依赖性疾病，影响生育期妇女。子宫内膜异位症是指“子宫内膜腺体在子宫外的异常生长”。已经提出了多种关于子宫内膜异位症发病机制的理论，Halban 的“良性转移”理论提出了在淋巴管和淋巴结中存在子宫内膜异位细胞，为这个病例报告提供了基础。在这里，我们报告了一例 26 岁的未产妇，她因卵巢癌的表现为在其主动脉旁淋巴结中存在子宫内膜异位症而导致 CA125 显著升高。