School of Biological Sciences, Institute of Evolutionary of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.
Department of Biology, University of Fribourg, Fribourg, Switzerland.
Mol Ecol. 2021 Aug;30(16):3896-3897. doi: 10.1111/mec.16026. Epub 2021 Jul 4.
Several recent publications have stated that epistatic fitness interactions cause the fixation of inversions that suppress recombination among the loci involved. Under this type of selection, however, the suppression of recombination in an inversion heterozygote can create a form of heterozygote advantage, which prevents the inversion from becoming fixed by selection. This process has been explicitly modelled by previous workers.
最近有几项研究指出，上位适合性相互作用导致了抑制涉及基因座之间重组的倒位的固定。然而，在这种选择类型下，倒位杂合体中重组的抑制可以产生一种杂合优势形式，从而阻止倒位通过选择而固定。这一过程已经被之前的研究人员明确建模。
