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儿童麻醉期间的中潜伏期听觉诱发电位：叙述性综述。

Midlatency auditory evoked potentials during anesthesia in children: A narrative review.

机构信息

Department of Anesthesiology, Erasmus MC Sophia Childrens Hospital, Rotterdam, The Netherlands.

Department of Anesthesiology, Haaglanden Medical Center, The Hague, The Netherlands.

出版信息

Paediatr Anaesth. 2021 Oct;31(10):1031-1039. doi: 10.1111/pan.14252. Epub 2021 Jul 18.

DOI:10.1111/pan.14252
PMID:34218499
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8518658/
Abstract

The brain is considered as the major target organ of anesthetic agents. Despite that, a reliable means to monitor its function during anesthesia is lacking. Mid latency auditory evoked potentials are known to be sensitive to anesthetic agents and might therefore be a measure of hypnotic state in pediatric patients. This review investigates the available literature describing various aspects of mid latency auditory evoked potential monitoring in pediatric anesthesia.

摘要

大脑被认为是麻醉剂的主要靶器官。尽管如此，在麻醉期间监测其功能的可靠方法仍然缺乏。中潜伏期听觉诱发电位已知对麻醉剂敏感，因此可能是小儿患者催眠状态的一种测量方法。本综述调查了描述小儿麻醉中中潜伏期听觉诱发电位监测各个方面的现有文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd4/8518658/a194719cc3c2/PAN-31-1031-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd4/8518658/9dce8abf11f5/PAN-31-1031-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd4/8518658/a194719cc3c2/PAN-31-1031-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd4/8518658/9dce8abf11f5/PAN-31-1031-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd4/8518658/a194719cc3c2/PAN-31-1031-g003.jpg

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1
Midlatency auditory evoked potentials during anesthesia in children: A narrative review.儿童麻醉期间的中潜伏期听觉诱发电位：叙述性综述。
Paediatr Anaesth. 2021 Oct;31(10):1031-1039. doi: 10.1111/pan.14252. Epub 2021 Jul 18.
2
Forty-hertz midlatency auditory evoked potential activity predicts wakeful response during desflurane and propofol anesthesia in volunteers.40赫兹中潜伏期听觉诱发电位活动可预测志愿者在七氟醚和丙泊酚麻醉期间的清醒反应。
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Evaluation of the auditory evoked potentials derived aepEX(™) as a measure of hypnotic depth in pediatric patients receiving sevoflurane-remifentanil anesthesia.评估源自aepEX(™)的听觉诱发电位，以此作为接受七氟烷-瑞芬太尼麻醉的儿科患者催眠深度的一种测量方法。
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Midlatency auditory evoked potentials do not allow the prediction of recovery from general anesthesia with isoflurane.中潜伏期听觉诱发电位无法预测异氟烷全身麻醉后的恢复情况。
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本文引用的文献

1
Population pharmacokinetic-pharmacodynamic model of propofol in adolescents undergoing scoliosis surgery with intraoperative wake-up test: a study using Bispectral index and composite auditory evoked potentials as pharmacodynamic endpoints.青少年脊柱侧弯手术中术中唤醒试验时依托咪酯的群体药代动力学-药效学模型：以双频谱指数和复合听觉诱发电位为药效终点的研究。
BMC Anesthesiol. 2019 Jan 22;19(1):15. doi: 10.1186/s12871-019-0684-z.
2
Monitoring Depth of Hypnosis: Mid-Latency Auditory Evoked Potentials Derived aepEX in Children Receiving Desflurane-Remifentanil Anesthesia.监测催眠深度：接受地氟烷-瑞芬太尼麻醉的儿童的中潜伏期听觉诱发电位 aepEX。
Anesth Analg. 2020 Jan;130(1):194-200. doi: 10.1213/ANE.0000000000003546.
3
Evaluation of the auditory evoked potentials derived aepEX(™) as a measure of hypnotic depth in pediatric patients receiving sevoflurane-remifentanil anesthesia.
评估源自aepEX(™)的听觉诱发电位，以此作为接受七氟烷-瑞芬太尼麻醉的儿科患者催眠深度的一种测量方法。
Paediatr Anaesth. 2014 Jul;24(7):760-5. doi: 10.1111/pan.12434. Epub 2014 May 12.
4
Evaluation of the aepEX™ monitor of hypnotic depth in pediatric patients receiving propofol-remifentanil anesthesia.在接受丙泊酚-瑞芬太尼麻醉的儿科患者中评估aepEX™催眠深度监测仪。
Paediatr Anaesth. 2013 Oct;23(10):891-7. doi: 10.1111/pan.12235. Epub 2013 Aug 2.
5
Impact of propofol on mid-latency auditory-evoked potentials in children.异丙酚对儿童中潜伏期听觉诱发电位的影响。
Br J Anaesth. 2013 Jun;110(6):1001-9. doi: 10.1093/bja/aet002. Epub 2013 Feb 10.
6
QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies.QUADAS-2：用于诊断准确性研究质量评估的修订工具。
Ann Intern Med. 2011 Oct 18;155(8):529-36. doi: 10.7326/0003-4819-155-8-201110180-00009.
7
Effects of increasing sevoflurane MAC levels on mid-latency auditory evoked potentials in infants, schoolchildren, and the elderly.七氟醚 MAC 水平升高对婴幼儿、学龄儿童和老年人中潜伏期听觉诱发电位的影响。
Br J Anaesth. 2011 Nov;107(5):726-34. doi: 10.1093/bja/aer226. Epub 2011 Jul 31.
8
Performance evaluation of paediatric propofol pharmacokinetic models in healthy young children.健康幼儿中儿童丙泊酚药代动力学模型的性能评估。
Br J Anaesth. 2011 Oct;107(4):593-600. doi: 10.1093/bja/aer198. Epub 2011 Jul 9.
9
The effect of cerebral monitoring on recovery after sevoflurane anesthesia in ambulatory setting in children: a comparison among bispectral index, A-line autoregressive index, and standard practice.脑监测对小儿七氟醚麻醉后恢复的影响：脑电双频指数、A 线自回归指数与常规监测的比较。
J Chin Med Assoc. 2011 Jan;74(1):28-36. doi: 10.1016/j.jcma.2011.01.004. Epub 2011 Jan 19.
10
Electroencephalography of infants under pentothal anesthesia.硫喷妥钠麻醉下婴儿的脑电图检查
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