Dermatology Department, Robert-Ballanger Hospital, boulevard Robert-Ballanger, 93600 Aulnay-sous-Bois, France.
Faculté de médecine, université de Paris, 15, rue de l'École de Médecine, 75006 Paris, France; Dermatology Department, Henri-Mondor University Hospital, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
Ann Dermatol Venereol. 2022 Mar;149(1):28-31. doi: 10.1016/j.annder.2021.04.007. Epub 2021 Jul 1.
Unlike other types of lichen planus (LP), there are no series concerning male genital LP.
To describe the clinical characteristics, diagnosis, and response to treatment of male genital LP.
A retrospective study of male patients with genital LP consulting a dermatologist specialized in anogenital diseases between January 2010 and 2019. Demographic data, history, functional signs, clinical characteristics, pathology, complications, and treatment efficacy were collected.
Eighty-nine patients were included at four centers. The median age was 51 years. Most patients were uncircumcised and asymptomatic. In 88.8% of cases, only the genital mucosa was involved. Erythema (71%), papules (21.3%), lacy network (15.7%), atrophic lesions (15.7%), erosions (14.6%), and post-inflammatory hyperpigmentation (2.2%) were less frequently observed. Biopsy results confirmed LP in 61.3% of cases but could not rule out other inflammatory genital dermatoses in other cases. Anatomic complications were observed in 30.3% of patients. Topical corticosteroids (TCS) induced remission in most cases. Tacrolimus efficacy was comparable to that of TCS.
Male genital LP is a rare inflammatory disorder chiefly affecting uncircumcised men. It is found predominantly on the mucosal component of the penis and presents as non-erosive inflammatory balanitis in most cases, with frequent partial or complete remission on treatment with TCS.
与其他类型的扁平苔藓（LP）不同，目前尚无关于男性生殖器 LP 的系列报道。
描述男性生殖器 LP 的临床特征、诊断和治疗反应。
对 2010 年 1 月至 2019 年期间咨询专门从事肛门生殖器疾病的皮肤科医生的男性生殖器 LP 患者进行回顾性研究。收集人口统计学数据、病史、功能体征、临床特征、病理、并发症和治疗效果。
在四个中心共纳入 89 例患者。中位年龄为 51 岁。大多数患者未行包皮环切术且无症状。88.8%的患者仅累及生殖器黏膜。红斑（71%）、丘疹（21.3%）、花边网络（15.7%）、萎缩性病变（15.7%）、糜烂（14.6%）和炎症后色素沉着（2.2%）较少见。活检结果在 61.3%的病例中证实为 LP，但在其他病例中不能排除其他炎症性生殖器皮肤病。30.3%的患者出现解剖并发症。局部皮质类固醇（TCS）诱导大多数患者缓解。他克莫司的疗效与 TCS 相当。
男性生殖器 LP 是一种罕见的炎症性疾病，主要影响未行包皮环切术的男性。它主要发生在阴茎的黏膜成分上，大多数情况下表现为非糜烂性炎症性龟头炎，大多数患者经 TCS 治疗后可部分或完全缓解。
