Fonsegrive J
Sem Hop. 1979;55(1-2):88-9.
The physiopathological processes involved in the production of dyskinesias will become clearer as our knowledge of neuromediators and their receptors increases. Among centrally-acting molecules, pimozide and the substituted benzamides block dopaminergic receptors only. Tiapride, which is a substituted benzamide, has an original neurotropic action expressed as relaxant and antidyskinetic activity. It is perfectly well-tolerated and is simple to prescribe, which has made it a product for use in general practice where very encouraging results have been obtained, especially in the two cases reported: an elderly patient with buccofacial dyskinesia often seen in this age group, and a patient with severe dopa-induced dyskinesias.