喉鳞状细胞癌中的独特核型异常

Unique karyotypic abnormalities in a squamous cell carcinoma of the larynx.

作者信息

Jin Y S, Mandahl N, Heim S, Biörklund A, Wennerberg J, Mitelman F

机构信息

Department of Clinical Genetics, Lund University Hospital, Sweden.

出版信息

Cancer Genet Cytogenet. 1988 Jan;30(1):177-9. doi: 10.1016/0165-4608(88)90109-4.

DOI:10.1016/0165-4608(88)90109-4

PMID:3422045

Abstract

We have cytogenetically examined short-term cultures from a squamous cell carcinoma of the larynx, a type of carcinoma in which chromosome aberrations have hitherto not been reported. The tumor karyotype was 46,XY,inv(2)(p22q24),t(9;13)(q34;q12),t(11;18)(q23;q21). None of these abnormalities have been described in carcinomas before.

摘要

我们对一例喉鳞状细胞癌的短期培养细胞进行了细胞遗传学检查，这种癌症类型迄今尚未有染色体畸变的报道。肿瘤核型为46,XY,inv(2)(p22q24),t(9;13)(q34;q12),t(11;18)(q23;q21)。这些异常在之前的癌症中均未被描述过。