髓内钉治疗胫骨骨干骨折后再次手术的中心量、外科医生量、外科医生经验和地理位置的影响。
Impact of centre volume, surgeon volume, surgeon experience and geographic location on reoperation after intramedullary nailing of tibial shaft fractures.
机构信息
From the Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minn. (Swiontkowski); the Department of Orthopedic Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, Okla. (Teague); the Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ont. (Sprague, Heels-Ansdell, Bhandari, Walter); the Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ont. (Sprague, Bzovsky, Bhandari); the Division of Orthopaedic Surgery, London Health Sciences Centre and Western University, London, Ont. (Schemitsch, Sanders); and the Department of Orthopedic Surgery, Boston Medical Center, Boston, Mass. (Tornetta).
London Health Sciences Centre/University of Western Ontario: David W. Sanders, Mark D. Macleod, Timothy Carey, Kellie Leitch, Stuart Bailey, Kevin Gurr, Ken Konito, Charlene Bartha, Isolina Low, Leila V. MacBean, Mala Ramu, Susan Reiber, Ruth Strapp, Christina Tieszer; Sunnybrook Health Sciences Centre/University of Toronto: Hans Kreder, David J.G. Stephen, Terry S. Axelrod, Albert J.M. Yee, Robin R. Richards, Joel Finkelstein, Richard M. Holtby, Hugh Cameron, John Cameron, Wade Gofton, John Murnaghan, Joseph Schatztker, Beverly Bulmer, Lisa Conlan; Hôpital du Sacré-Coeur de Montréal: Yves Laflamme, Gregory Berry, Pierre Beaumont, Pierre Ranger, Georges-Henri Laflamme, Alain Jodoin, Eric Renaud, Sylvain Gagnon, Gilles Maurais, Michel Malo, Julio Fernandes, Kim Latendresse, Marie-France Poirier, Gina Daigneault; St. Michael’s Hospital/University of Toronto: Emil H. Schemitsch, Michael M. McKee, James P. Waddell, Earl R. Bogoch, Timothy R. Daniels, Robert R. McBroom, Robin R. Richards, Milena R. Vicente, Wendy Storey, Lisa M. Wild; Royal Columbian Hospital/University of British Columbia, Vancouver: Robert McCormack, Bertrand Perey, Thomas J. Goetz, Graham Pate, Murray J. Penner, Kostas Panagiotopoulos, Shafique Pirani, Ian G. Dommisse, Richard L. Loomer, Trevor Stone, Karyn Moon, Mauri Zomar; Wake Forest Medical Center/Wake Forest University Health Sciences, Winston-Salem, NC: Lawrence X. Webb, Robert D. Teasdall, John Peter Birkedal, David F. Martin, David S. Ruch, Douglas J. Kilgus, David C. Pollock, Mitchel Brion Harris, Ethan R. Wiesler, William G. Ward, Jeffrey Scott Shilt, Andrew L. Koman, Gary G. Poehling, Brenda Kulp; Boston Medical Center/Boston University School of Medicine: Paul Tornetta III, William R. Creevy, Andrew B. Stein, Christopher T. Bono, Thomas A. Einhorn, T. Desmond Brown, Donna Pacicca, John B. Sledge III, Timothy E. Foster, Ilva Voloshin, Jill Bolton, Hope Carlisle, Lisa Shaughnessy; Wake Medical Center, Raleigh, NC: William T. Ombremsky, C. Michael LeCroy, Eric G. Meinberg, Terry M. Messer, William L. Craig III, Douglas R. Dirschl, Robert Caudle, Tim Harris, Kurt Elhert, William Hage, Robert Jones, Luis Piedrahita, Paul O. Schricker, Robin Driver, Jean Godwin, Gloria Hansley; Vanderbilt University Medical Center, Nashville, Tenn.: William T. Obremskey, Philip J. Kregor, Gregory Tennent, Lisa M. Truchan, Marcus Sciadini, Franklin D. Shuler, Robin E. Driver, Mary Alice Nading, Jacky Neiderstadt, Alexander R. Vap; MetroHealth Medical Center, Cleveland: Heather A. Vallier, Brendan M. Patterson, John H. Wilber, Roger G. Wilber, John K. Sontich, Timothy A. Moore, Drew Brady, Daniel R. Cooperman, John A. Davis, Beth Ann Cureton; Hamilton Health Sciences, Hamilton, Ont.: Scott Mandel, R. Douglas Orr, John T.S. Sadler, Tousief Hussain, Krishan Rajaratnam, Bradley Petrisor, Mohit Bhandari, Brian Drew, Drew A. Bednar, Desmond C.H. Kwok, Shirley Pettit, Jill Hancock, Natalie Sidorkewicz; Regions Hospital, Saint Paul, Minn.: Peter A. Cole, Joel J. Smith, Gregory A. Brown, Thomas A. Lange, John G. Stark, Bruce Levy, Marc Swiontkowski, Julie Agel, Mary J. Garaghty, Joshua G. Salzman, Carol A. Schutte, Linda (Toddie) Tastad, Sandy Vang; University of Louisville School of Medicine, Louisville, Ky.: David Seligson, Craig S. Roberts, Arthur L. Malkani, Laura Sanders, Sharon Allen Gregory, Carmen Dyer, Jessica Heinsen, Langan Smith, Sudhakar Madanagopal; Memorial Hermann Hospital, Houston: Kevin J. Coupe, Jeffrey J. Tucker, Allen R. Criswell, Rosemary Buckle, Alan Jeffrey Rechter, Dhiren Shaskikant Sheth, Brad Urquart, Thea Trotscher; Erie County Medical Center/University of Buffalo, Buffalo, NY: Mark J. Anders, Joseph M. Kowalski, Marc S. Fineberg, Lawrence B. Bone, Matthew J. Phillips, Bernard Rohrbacher, Philip Stegemann, William M. Mihalko, Cathy Buyea; University of Florida – Jacksonville: Stephen J. Augustine, William Thomas Jackson, Gregory Solis, Sunday U. Ero, Daniel N. Segina, Hudson B. Berrey, Samuel G. Agnew, Michael Fitzpatrick, Lakina C. Campbell, Lynn Derting, June McAdams; Academic Medical Center, Amsterdam: J. Carel Goslings, Kees Jan Ponsen, Jan Luitse, Peter Kloen, Pieter Joosse, Jasper Winkelhagen, Raphaël Duivenvoorden; University of Oklahoma Health Science Center, Oklahoma City: David C. Teague, Joseph Davey, J. Andy Sullivan, William J.J. Ertl, Timothy A. Puckett, Charles B. Pasque, John F. Tompkins II, Curtis R. Gruel, Paul Kammerlocher, Thomas P. Lehman, William R. Puffinbarger, Kathy L. Carl; University of Alberta/University of Alberta Hospital, Edmonton: Donald W. Weber, Nadr M. Jomha, Gordon R. Goplen, Edward Masson, Lauren A. Beaupre, Karen E. Greaves, Lori N. Schaump; Greenville Hospital System, Greenville, SC: Kyle J. Jeray, David R. Goetz, Davd E. Westberry, J. Scott Broderick, Bryan S. Moon, Stephanie L. Tanner; Foothills General Hospital, Calgary: James N. Powell, Richard E. Buckley, Leslie Elves; Saint John Regional Hospital, Saint John, NB: Stephen Connolly, Edward P. Abraham, Donna Eastwood, Trudy Steele; Oregon Health & Science University, Portland: Thomas Ellis, Alex Herzberg, George A. Brown, Dennis E. Crawford, Robert Hart, James Hayden, Robert M. Orfaly, Theodore Vigland, Maharani Vivekaraj, Gina L. Bundy; San Francisco General Hospital: Theodore Miclau III, Amir Matityahu, R. Richard Coughlin, Utku Kandemir, R. Trigg McClellan, Cindy Hsin-Hua Lin; Detroit Receiving Hospital: David Karges, Kathryn Cramer, J. Tracy Watson, Berton Moed, Barbara Scott; Deaconess Hospital Regional Trauma Center and Orthopaedic Associates, Evansville, Ind.: Dennis J. Beck, Carolyn Orth; Thunder Bay Regional Health Sciences Centre, Thunder Bay, Ont.: David Puskas, Russell Clark, Jennifer Jones; Jamaica Hospital, Jamaica, NY: Kenneth A. Egol, Nader Paksima, Monet France; Ottawa Hospital – Civic Campus: Eugene K. Wai, Garth Johnson, Ross Wilkinson, Adam T. Gruszczynski, Liisa Vexler.
出版信息
Can J Surg. 2021 Jul 5;64(4):E371-E376. doi: 10.1503/cjs.004020.
BACKGROUND
Tibial shaft fractures are the most common long-bone injury, with a reported annual incidence of more than 75 000 in the United States. This study aimed to determine whether patients with tibial fractures managed with intramedullary nails experience a lower rate of reoperation if treated at higher-volume hospitals, or by higher-volume or more experienced surgeons.
METHODS
The Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures (SPRINT) was a multicentre randomized clinical trial comparing reamed and nonreamed intramedullary nailing on rates of reoperation to promote fracture union, treat infection or preserve the limb in patients with open and closed fractures of the tibial shaft. Using data from SPRINT, we quantified centre and surgeon volumes into quintiles. We performed analyses adjusted for type of fracture (open v. closed), type of injury (isolated v. multitrauma), gender and age for the primary outcome of reoperation using multivariable logistic regression.
RESULTS
There were no significant differences in the odds of reoperation between high- and low-volume centres (p = 0.9). Overall, surgeon volume significantly affected the odds of reoperation (p = 0.03). The odds of reoperation among patients treated by moderate-volume surgeons were 50% less than those among patients treated by verylow-volume surgeons (odds ratio [OR] 0.50, 95% confidence interval [CI] 0.28–0.88), and the odds of reoperation among patients treated by high-volume surgeons were 47% less than those among patients treated by very-low-volume surgeons (OR 0.53, 95% CI 0.30–0.93).
CONCLUSION
There appears to be no significant additional patient benefit in treatment by a higher-volume centre for intramedullary fixation of tibial shaft fractures. Additional research on the effects of surgical and clinical site volume in tibial shaft fracture management is needed to confirm this finding. The odds of reoperation were higher in patients treated by very-low-volume surgeons; this finding may be used to optimize the results of tibial shaft fracture management. Clinical trial registration: ClinicalTrials.gov, NCT00038129
背景
胫骨骨折是最常见的长骨损伤，据报道，在美国每年的发病率超过 75000 例。本研究旨在确定接受髓内钉治疗的胫骨骨折患者，如果在高容量医院或由高容量或更有经验的外科医生治疗，是否会降低再次手术的发生率。
方法
前瞻性评估胫骨骨折患者扩髓髓内钉治疗（SPRINT）研究是一项多中心随机临床试验，比较扩髓和非扩髓髓内钉治疗胫骨骨干开放性和闭合性骨折患者骨折愈合、治疗感染或保留肢体的再手术率。利用 SPRINT 数据，我们将中心和外科医生的数量分为五组。我们使用多变量逻辑回归分析，对骨折类型（开放性与闭合性）、损伤类型（单一创伤与多发创伤）、性别和年龄进行调整，分析主要转归再手术的概率。
结果
高容量和低容量中心之间再手术的几率没有显著差异（p = 0.9）。总体而言，外科医生的数量显著影响再手术的几率（p = 0.03）。与超低容量外科医生治疗的患者相比，中等容量外科医生治疗的患者再手术的几率降低了 50%（比值比 [OR] 0.50，95%置信区间 [CI] 0.28-0.88），高容量外科医生治疗的患者再手术的几率降低了 47%（OR 0.53，95% CI 0.30-0.93）。
结论
对于胫骨骨干骨折的髓内固定治疗，在高容量中心治疗似乎没有显著增加患者的获益。需要进一步研究手术和临床部位数量对胫骨骨折管理的影响，以证实这一发现。接受超低容量外科医生治疗的患者再手术的几率较高；这一发现可用于优化胫骨骨折管理的结果。临床试验注册：ClinicalTrials.gov，NCT00038129
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