Wilding Sarah, Kettu Virpi, Thompson Wendy, Howard Philip, Jeuken Lars J C, Pownall Madeleine, Conner Mark, Sandoe Jonathan A T
School of Psychology, University of Leeds, Leeds, UK.
Kettu Studios, Skipton, UK.
JAC Antimicrob Resist. 2021 Jun 17;3(2):dlab083. doi: 10.1093/jacamr/dlab083. eCollection 2021 Jun.
Antimicrobial resistance (AMR) is a global health crisis but reducing antibiotic use can help. Some antibiotic use is driven by patient demand.
To develop an intervention to discourage antibiotic-seeking behaviour in adults.
Literature reviewed to identify behaviours for acquiring antibiotics among adults in the community. Behaviour change wheel approach was used to select the target behaviour and behaviour change techniques. An intervention in the form of a short animated film was developed and its potential impact evaluated in a randomized, controlled, online questionnaire study.
Asking a general medical/dental practitioner for antibiotics was identified as the target behaviour. A short stop-motion animated film was chosen to deliver several behaviour-change techniques. Education and persuasion were delivered around information about the normal microbial flora, its importance for health, the negative effect of antibiotics, and about AMR. 417 UK-based individuals completed the questionnaire; median age 34.5 years, 71% female, 91% white ethnicity. 3.8% of participants viewing the test film intended to ask for antibiotics compared with 7.9% viewing the control film. Test film viewers had significantly higher knowledge scores. At 6 week follow up, knowledge scores remained significantly different, while most attitude and intention scores were not different.
Some patients continue to ask for antibiotics. The film increased knowledge and reduced intentions to ask for antibiotics. At 6 weeks, knowledge gains remained but intentions not to ask for antibiotics had waned. Evaluation in the clinical environment, probably at the point of care, is needed to see if antibiotic prescribing can be impacted.
抗菌药物耐药性（AMR）是一场全球健康危机，但减少抗生素使用会有所帮助。一些抗生素的使用是由患者需求驱动的。
开发一种干预措施，以抑制成年人寻求抗生素的行为。
查阅文献以确定社区中成年人获取抗生素的行为。采用行为改变轮方法选择目标行为和行为改变技术。制作了一部简短的动画电影形式的干预措施，并在一项随机对照在线问卷调查研究中评估其潜在影响。
向普通医疗/牙科医生索要抗生素被确定为目标行为。选择了一部简短的定格动画电影来传达几种行为改变技术。围绕正常微生物群及其对健康的重要性、抗生素的负面影响以及抗菌药物耐药性等信息进行教育和劝导。417名英国居民完成了问卷调查；中位年龄34.5岁，71%为女性，91%为白人。观看测试影片的参与者中有3.8%打算索要抗生素，而观看对照影片的这一比例为7.9%。测试影片观看者的知识得分显著更高。在6周随访时，知识得分仍有显著差异，而大多数态度和意图得分没有差异。
一些患者仍在索要抗生素。该影片增加了知识并降低了索要抗生素的意愿。在6周时，知识增益仍然存在，但不索要抗生素的意愿有所减弱。需要在临床环境中，可能在护理点进行评估，以查看是否会对抗生素处方产生影响。
