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创伤性脑损伤中的减压性颅骨切除术:两年内131例的机构经验

Decompressive Craniectomy in Traumatic Brain Injury: An Institutional Experience of 131 Cases in Two Years.

作者信息

Silva Ana Cristina Veiga, de Oliveira Farias Matheus Araújo, Bem Luiz Severo, Valença Marcelo Moraes, de Azevedo Filho Hildo Rocha Cirne

机构信息

Department of Neuropsychiatry and Behavioral Sciences, Federal University of Pernambuco, Recife, Brazil.

School of Medicine, Federal University of Pernambuco, Recife, Brazil.

出版信息

Neurotrauma Rep. 2020 Oct 7;1(1):93-99. doi: 10.1089/neur.2020.0007. eCollection 2020.

Abstract

Decompressive craniectomy (DC) effectively reduces intracranial pressure (ICP), but is not considered to be a first-line procedure. We retrospectively analyzed sociodemographic, clinical, and surgical characteristics associated with the prognosis of patients who underwent DC to treat traumatic intracranial hypertension (ICH) at the Restauração Hospital (HR) in Recife, Brazil between 2015 and 2016, and compared the clinical features with surgical timing and functional outcome at discharge. The data were collected from 131 medical records in the hospital database. A significant majority of the patients were young adults (age 18-39 years old; 75/131; 57.3%) and male (118/131; 90.1%). Road traffic accidents, particularly those involving motorcycles (57/131; 44.5%), were the main cause of the traumatic event. At initial evaluation, 63 patients (48.8%) were classified with severe traumatic brain injury (TBI). Pupil examination showed no abnormalities for 91 patients (71.1%), and acute subdural hematoma was the most frequently observed lesion (83/212; 40%). Glasgow Outcome Scale (GOS) score was used to categorize surgical results and 51 patients (38.9%) had an unfavorable outcome. Only the Glasgow Coma Scale (GCS) score on admission (score of 3-8) was more likely to be associated with unfavorable outcome (-value = 0.009), indicating that this variable may be a determinant of mortality and prognostic of poor outcome. Patients who underwent an operation sooner after injury, despite having a worse condition on admission, presented with clinical results that were similar to those of patients who underwent surgery 12 h after hospital admission. These results emphasize the importance of early DC for management of severe TBI. This study shows that DC is a common procedure used to manage TBI patients at HR.

摘要

减压性颅骨切除术(DC)能有效降低颅内压(ICP),但不被视为一线治疗手段。我们回顾性分析了2015年至2016年期间在巴西累西腓的雷斯塔劳医院(HR)接受DC治疗创伤性颅内高压(ICH)患者的社会人口统计学、临床和手术特征,并比较了临床特征与手术时机及出院时的功能结局。数据收集自医院数据库中的131份病历。绝大多数患者为年轻成年人(18 - 39岁;75/131;57.3%)且为男性(118/131;90.1%)。道路交通事故,尤其是涉及摩托车的事故(57/131;44.5%),是创伤事件的主要原因。在初次评估时,63名患者(48.8%)被归类为重度创伤性脑损伤(TBI)。瞳孔检查显示91名患者(71.1%)无异常,急性硬膜下血肿是最常见的损伤(83/212;40%)。格拉斯哥预后量表(GOS)评分用于对手术结果进行分类,51名患者(38.9%)预后不良。仅入院时的格拉斯哥昏迷量表(GCS)评分(3 - 8分)更有可能与不良预后相关(P值 = 0.009),表明该变量可能是死亡率和不良预后的决定因素。受伤后尽早接受手术的患者,尽管入院时病情更严重,但其临床结果与入院12小时后接受手术的患者相似。这些结果强调了早期DC对重度TBI管理的重要性。本研究表明DC是HR用于管理TBI患者的常见手术。

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