Caries inhibition of mixed NaF-Na2PO3F dentifrices containing 1,000 and 2,500 ppm F: 3-year results.

The 3-year DMFS increments of 2,509 children were compared. Group 1 used a conventional Na2PO3F dentifrice (1,000 ppm F) and served as the active control. Groups 2 and 3 used mixed-fluoride dentifrices containing equimolar amounts of NaF and Na2PO3F, providing total fluoride concentrations of 1,000 and 2,500 ppm F, respectively. Dentifrice use was unsupervised in the subjects' homes. There were no statistically significant differences (F-test) between the 3-year DMFS increments of the dentifrice groups, nor were there any significant differences between the dentifrice groups when the analysis included subject compliance and caries risk.