• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Fractionation of COVID-19 vaccine doses could extend limited supplies and reduce mortality.

作者信息

Cowling Benjamin J, Lim Wey Wen, Cobey Sarah

机构信息

World Health Organization Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.

Laboratory of Data Discovery for Health Limited, Hong Kong Science and Technology Park, New Territories, Hong Kong Special Administrative Region, Hong Kong, China.

出版信息

Nat Med. 2021 Aug;27(8):1321-1323. doi: 10.1038/s41591-021-01440-4.

DOI:10.1038/s41591-021-01440-4
PMID:34226735
Abstract
摘要

相似文献

1
Fractionation of COVID-19 vaccine doses could extend limited supplies and reduce mortality.分剂接种新冠疫苗可延长有限的供应并降低死亡率。
Nat Med. 2021 Aug;27(8):1321-1323. doi: 10.1038/s41591-021-01440-4.
2
How can countries stretch COVID vaccine supplies? Scientists are divided over dosing strategies.各国如何延长新冠疫苗供应？科学家们在给药策略上存在分歧。
Nature. 2021 Jan;589(7841):182. doi: 10.1038/d41586-021-00001-6.
3
Rationing of Civilian Coronavirus Disease 2019 Vaccines While Supplies Are Limited.2019年新型冠状病毒病疫苗在供应有限时的分配
J Infect Dis. 2020 Nov 9;222(11):1776-1779. doi: 10.1093/infdis/jiaa569.
4
India's COVID-vaccine woes - by the numbers.印度新冠疫苗困境——数据说明一切。
Nature. 2021 Apr;592(7855):500-501. doi: 10.1038/d41586-021-00996-y.
5
How COVID vaccines shaped 2021 in eight powerful charts.新冠疫苗如何通过八张有力图表塑造了2021年。
Nature. 2021 Dec;600(7890):580-583. doi: 10.1038/d41586-021-03686-x.
6
Cash payments in Africa could boost vaccine uptake.在非洲进行现金支付可能会提高疫苗接种率。
Nature. 2021 Aug;596(7870):9. doi: 10.1038/d41586-021-02086-5.
7
Inequitable COVID-19 vaccine distribution and its effects.不公平的新冠疫苗分配及其影响。
Bull World Health Organ. 2021 Jun 1;99(6):406-406A. doi: 10.2471/BLT.21.285616.
8
Intradermal covid-19 vaccination could solve supply problems.皮内注射新冠疫苗可以解决供应问题。
BMJ. 2021 Aug 16;374:n1980. doi: 10.1136/bmj.n1980.
9
COVID-19: SARS-CoV-2 Vaccine-Induced Immune Thrombotic Thrombocytopenia.新型冠状病毒肺炎：严重急性呼吸综合征冠状病毒2疫苗诱导的免疫性血栓性血小板减少症
Hamostaseologie. 2021 Jun;41(3):179-182. doi: 10.1055/a-1369-3488. Epub 2021 Jun 30.
10
Reflections on SARS-CoV-2 new strain contagiousness and its prevention with mRNA vaccines.关于严重急性呼吸综合征冠状病毒2（SARS-CoV-2）新毒株传染性及其mRNA疫苗预防的思考
Gac Med Mex. 2021;157(3):318. doi: 10.24875/GMM.M21000565.

引用本文的文献

1
Safety and immunogenicity of fractional COVID-19 vaccine doses in Nigerian adults: A randomized non-inferiority trial.尼日利亚成年人中新冠病毒疫苗分剂量接种的安全性和免疫原性：一项随机非劣效性试验。
Sci Rep. 2025 Jul 29;15(1):27614. doi: 10.1038/s41598-025-06536-2.
2
Predicting Efficacies of Fractional Doses of Vaccines by Using Neutralizing Antibody Levels: Systematic Review and Meta-Analysis.利用中和抗体水平预测疫苗的分剂量疗效：系统评价和荟萃分析。
JMIR Public Health Surveill. 2024 Jul 12;10:e49812. doi: 10.2196/49812.
3
Immunogenicity, safety, and reactogenicity of a half- versus full-dose BNT162b2 (Pfizer-BioNTech) booster following a two-dose ChAdOx1 nCoV-19, BBIBP-CorV, or Gam-COVID-Vac priming schedule in Mongolia: a randomised, controlled, non-inferiority trial.
在蒙古，采用两剂ChAdOx1 nCoV-19、BBIBP-CorV或Gam-COVID-Vac进行初始接种后，半剂量与全剂量BNT162b2（辉瑞-生物科技公司）加强针的免疫原性、安全性和反应原性：一项随机、对照、非劣效性试验。
Lancet Reg Health West Pac. 2023 Nov 21;42:100953. doi: 10.1016/j.lanwpc.2023.100953. eCollection 2024 Jan.
4
Targeted randomization dose optimization trials enable fractional dosing of scarce drugs.靶向随机化剂量优化试验可实现稀缺药物的分数剂量给药。
PLoS One. 2023 Oct 30;18(10):e0287511. doi: 10.1371/journal.pone.0287511. eCollection 2023.
5
Cost effectiveness of fractional doses of COVID-19 vaccine boosters in India.印度 COVID-19 疫苗加强针的分剂次成本效益。
Med. 2023 Mar 10;4(3):182-190.e3. doi: 10.1016/j.medj.2023.02.001. Epub 2023 Feb 13.
6
Modeling the spread dynamics of multiple-variant coronavirus disease under public health interventions: A general framework.公共卫生干预下多变异株冠状病毒病传播动力学建模：一个通用框架
Inf Sci (N Y). 2023 May;628:469-487. doi: 10.1016/j.ins.2023.02.001. Epub 2023 Feb 6.
7
Role of vaccine in fighting the variants of COVID-19.疫苗在抗击新冠病毒变种中的作用。
Chaos Solitons Fractals. 2023 Mar;168:113159. doi: 10.1016/j.chaos.2023.113159. Epub 2023 Jan 18.
8
Immunogenicity of a fractional or full third dose of AZD1222 vaccine or BNT162b2 messenger RNA vaccine after two doses of CoronaVac vaccines against the Delta and Omicron variants.两剂科兴疫苗接种后接种一剂或两剂 AZD1222 疫苗或 BNT162b2 信使 RNA 疫苗对德尔塔和奥密克戎变异株的免疫原性。
Int J Infect Dis. 2023 Apr;129:19-31. doi: 10.1016/j.ijid.2023.01.022. Epub 2023 Jan 20.
9
Perception of Availability, Accessibility, and Affordability of COVID-19 Vaccines and Hesitancy: A Cross-Sectional Study in India.对2019冠状病毒病疫苗可及性、可获取性、可负担性的认知及犹豫态度：印度的一项横断面研究
Vaccines (Basel). 2022 Nov 25;10(12):2009. doi: 10.3390/vaccines10122009.
10
Immunogenicity, efficacy, and safety of SARS-CoV-2 vaccine dose fractionation: a systematic review and meta-analysis.SARS-CoV-2 疫苗剂量分割的免疫原性、疗效和安全性：系统评价和荟萃分析。
BMC Med. 2022 Oct 25;20(1):409. doi: 10.1186/s12916-022-02600-0.