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胃旁路术后报告疑似问题饮酒行为患者的特征:BAROBS 研究的长期数据分析。

Characteristics of Patients Reporting Presumed Problematic Drinking Behavior After Gastric Bypass: Exploring Long-Term Data From the BAROBS Study.

机构信息

Centre for Obesity Research, Clinic of Surgery, St. Olavs University Hospital, Trondheim, Norway.

Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

出版信息

Front Endocrinol (Lausanne). 2021 Jun 18;12:679006. doi: 10.3389/fendo.2021.679006. eCollection 2021.

Abstract

OBJECTIVE

To explore patients' long-term experiences with drinking alcohol after Roux-n-Y gastric bypass (RYGB) for conceptualizing what may indicate problematic drinking behavior after bariatric surgery.

STUDY DESIGN

Three-center, observational study.

PATIENTS

546 adult patients undergoing RYGB in the period 2003-2009 in Norway.

MAIN OUTCOME MEASURES

Self-reported data on drinking behavior and experiences related to alcohol collected 10-15 years after surgery.

RESULTS

Out of the 959 patients undergoing RYGB in the period, 29 were diseased and 546 participated in this follow-up study (58.7%). Focusing on suspicious changes in drinking behavior, 8.8% reported drinking more, 11.5% consumed alcohol at least twice a week, and 10.6% consumed at a minimum of 6 units of alcohol at a frequency of at least once monthly. The nature of hangovers had changed for about a third of the patients, with 21.6% reporting these to feel weaker or absent. Repeated alcoholic blackouts were reported by 11.9%. A subgroup of the patients were categorized as displaying presumed problematic drinking behavior(PPDB). Among the PPDB-men there was a significant association to having had a fall last year (6 (100.0%) PPDB-patients 30 (29.7%) non-PPDB, p<.001). Among the PPDB-women, there was a significant association to having had alcohol problems prior to surgery (7 (70.0%) PPDB-patients 67 (17.7%) non-PPDB, p<.001). Less significant associations to PPDB reported for explorative purposes were lack of patient education (men) (16 (26.2%) PPDB-patients 8 (61.5%) non-PPDB, p=.014); more than 3 months persistent musculoskeletal pain (women) (45 (15.3%) PPDB-patients 29 (24.6%) non-PPDB, p=.026); subjective problems with memory (women) (58 (20.7%) PPDB-patients 10 (9.1%) non-PPDB, p=.006); and, receiving professional help for mental problems last 12 months (women) (29 (22.7%) PPDB-patients 45 (14.7%) non-PPDB, p=.043).

CONCLUSION

A subset of patients display drinking behaviors that may be consistent with postsurgical alcohol problems. Screening instruments like AUDIT may not be sufficiently specific to capture several risk behaviors occurring after bariatric surgery.

摘要

目的

通过探索接受 Roux-en-Y 胃旁路术(RYGB)后患者长期饮酒的体验,对肥胖症手术后可能出现的饮酒问题行为进行概念化。

研究设计

三中心观察性研究。

患者

2003-2009 年期间在挪威接受 RYGB 的 546 名成年患者。

主要观察指标

术后 10-15 年收集的与饮酒行为及与酒精相关的体验相关的自我报告数据。

结果

在接受 RYGB 的 959 例患者中,29 例患有疾病,546 例参加了本随访研究(58.7%)。在可疑饮酒行为改变方面,8.8%的患者报告饮酒量增加,11.5%的患者每周至少饮酒两次,10.6%的患者每月至少饮酒 6 次。大约三分之一患者的宿醉性质发生了变化,21.6%的患者报告宿醉感觉更弱或不存在。11.9%的患者报告出现反复性酒精性昏迷。一小部分患者被归类为表现出疑似饮酒问题行为(PPDB)。在 PPDB 男性中,去年跌倒的显著相关(6(100.0%)PPDB 患者 30(29.7%)非 PPDB,p<.001)。在 PPDB 女性中,术前有酒精问题的显著相关(7(70.0%)PPDB 患者 67(17.7%)非 PPDB,p<.001)。为了探索目的,报告了与 PPDB 相关的不太显著的关联包括缺乏患者教育(男性)(16(26.2%)PPDB 患者 8(61.5%)非 PPDB,p=.014);持续 3 个月以上的肌肉骨骼疼痛(女性)(45(15.3%)PPDB 患者 29(24.6%)非 PPDB,p=.026);主观记忆问题(女性)(58(20.7%)PPDB 患者 10(9.1%)非 PPDB,p=.006);以及,过去 12 个月接受心理健康专业帮助(女性)(29(22.7%)PPDB 患者 45(14.7%)非 PPDB,p=.043)。

结论

一部分患者表现出的饮酒行为可能与术后酒精问题一致。AUDIT 等筛查工具可能无法充分捕捉到肥胖症手术后出现的几种风险行为。

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