Bowman J M, Levy B A, Grubb R V
Department of Oral Pathology, Baltimore College of Dental Surgery, University of Maryland.
Oral Surg Oral Med Oral Pathol. 1988 Feb;65(2):183-5. doi: 10.1016/0030-4220(88)90163-6.
Gingival overgrowth induced by diphenylhydantoin (Dilantin) has been well documented in the literature. Recently, there have been other medications with side effects causing Dilantin-like gingival overgrowth. This article presents a case in which diltiazem (Cardizem), a calcium-channel blocker, induced gingival overgrowth. A discussion of the clinical and histologic features and possible pathogenesis of the disorder is presented.
文献中已充分记载了由苯妥英钠（大仑丁）引起的牙龈增生。最近，有其他药物也有导致类似大仑丁所致牙龈增生的副作用。本文介绍了一例由钙通道阻滞剂地尔硫䓬（合心爽）引起牙龈增生的病例，并对该病症的临床和组织学特征以及可能的发病机制进行了讨论。
