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急性蛛网膜下腔出血中采用新一代支架进行双重支架治疗动脉瘤栓塞。

Dual Stenting with New-Generation Stents for Aneurysm Embolization in Acute Subarachnoid Hemorrhage.

机构信息

Department of Interventional Radiology, Ankara Bilkent City Hospital, Ankara, Turkey.

Department of Neurosurgery, Ankara Bilkent City Hospital, Ankara, Turkey.

出版信息

World Neurosurg. 2021 Oct;154:e102-e108. doi: 10.1016/j.wneu.2021.06.135. Epub 2021 Jul 3.

Abstract

OBJECTIVE

Endosaccular treatment is the backbone of endovascular treatment for acutely ruptured aneurysms. Stent-assisted coiling is a niche technique in this context. Data on X-stenting or Y-stenting (dual crossing stenting, DCS) in the acute phase after subarachnoid hemorrhage (aSAH) are scarce, and the impact of stent properties on the outcome is unknown. We retrospectively evaluated the clinical and imaging results of DCS in patients treated for aSAH.

METHODS

Patients with aSAH treated with DCS were evaluated retrospectively. Patient and procedural characteristics were evaluated to determine clinical outcomes, associated complications, and follow-up imaging findings.

RESULTS

Sixteen procedures (16 patients; 10 women, mean age 55.8) were performed within 3.2 ± 2.6 days (range 1-10 days) of aSAH. Only the latest generation of intracranial stents (dual Neuroform Atlas-12 cases, dual Leo Baby-2 cases, Neuroform Atlas with Acclino Flex, or Leo Baby-2 cases) were used. Technical success rate was 100%; however, 25% of the procedures were complicated, leading to adverse events in 3 procedures (18.8%; 2 stent thrombosis, 1aneurysm rupture). Procedure-related morbidity and mortality and overall permanent morbidity and mortality were 6.3%, none, 6.3%, and 12.5%, respectively. No additional neurologic events were noted on a mean clinical follow-up of 160 ± 156 (range: 1-540) days.

CONCLUSIONS

Our findings and the patient-by-patient data we extracted from the literature suggest that DCS can be performed with new-generation, low-profile stents in aSAH if a definite procedural risk is acceptable for a specific patient. New-generation open-cell stent combinations appear as a viable choice for DCS in aSAH.

摘要

目的

血管内治疗急性破裂动脉瘤的核心是瘤内治疗。支架辅助弹簧圈栓塞术是该背景下的一种专业技术。蛛网膜下腔出血(SAH)后急性期 X 支架或 Y 支架(双交叉支架,DCS)的数据很少,支架特性对结果的影响尚不清楚。我们回顾性评估了 DCS 在治疗 SAH 患者中的临床和影像学结果。

方法

回顾性评估接受 DCS 治疗的 SAH 患者。评估患者和手术特点,以确定临床结果、相关并发症和随访影像学发现。

结果

16 例(16 例患者;10 例女性,平均年龄 55.8 岁)在蛛网膜下腔出血后 3.2±2.6 天(范围 1-10 天)内行 DCS。仅使用最新一代颅内支架(双 Neuroform Atlas-12 例,双 Leo Baby-2 例,Neuroform Atlas 与 Acclino Flex 或 Leo Baby-2 例)。技术成功率为 100%;然而,25%的手术出现并发症,导致 3 例出现不良事件(18.8%;2 例支架血栓形成,1 例动脉瘤破裂)。与手术相关的发病率和死亡率以及总永久性发病率和死亡率分别为 6.3%、0、6.3%和 12.5%。在平均 160±156 天(范围:1-540 天)的临床随访中,未发现其他新的神经事件。

结论

我们的发现和从文献中提取的每个患者的数据表明,如果特定患者的特定手术风险可以接受,那么在 SAH 中可以使用新一代、低轮廓支架进行 DCS。新一代开环支架组合似乎是 SAH 中 DCS 的可行选择。

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