Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.
Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; National Institute for Health Research Health Protection Research Unit (NIHR-HPRU) in Immunisation, London School of Hygiene & Tropical Medicine in partnership with Public Health England, London, UK.
Vaccine. 2021 Jul 30;39(33):4700-4704. doi: 10.1016/j.vaccine.2021.06.039. Epub 2021 Jul 3.
Maternal immunization is key to protecting maternal and newborn health. We interviewed pregnant women in Brazil to identify barriers to and enablers of maternal immunization in the country. In-depth interviews and focus groups were conducted in Brazil with 60 pregnant women from São Paulo and Rio de Janeiro at different stages of their pregnancies. Participants were encouraged to discuss views on safety, efficacy and importance of maternal vaccines, access to vaccines, interactions with healthcare professionals, and sources of information on vaccine-related matters. There was generally a positive regard for maternal immunization among the interviewed women, many of whom associated vaccination with protection of their unborn child. The interviewees cited several reasons for adherence to immunization guidelines, including recommendations from healthcare professionals, targeted communication campaigns, and active use of a vaccination card or booklet. There were no reported barriers for maternal vaccines. Some women using private healthcare services reported not having been asked about vaccines at check-ups, which could adversely affect vaccination rates. A rumour that vaccines caused microcephaly which emerged during the Zika outbreak was the most commonly cited reason for choosing not to vaccinate among the interviewees. This study identified important vaccine confidence builders. Many of the interviewees critically reflected upon information received, placing themselves as the decision makers over their health choices. A prominent barrier to maternal immunization was a rumour linking vaccines to microcephaly. To the best of our knowledge, this has not been previously reported in the literature and requires further investigation into the extent of this issue and how it can be mitigated.
译文: 母体免疫是保护母婴健康的关键。我们采访了巴西的孕妇,以了解该国阻碍和促进母体免疫的因素。在巴西,研究人员在圣保罗和里约热内卢对处于不同妊娠阶段的 60 名孕妇进行了深入访谈和焦点小组讨论。研究人员鼓励参与者讨论对母体疫苗的安全性、有效性和重要性、疫苗获取、与医疗保健专业人员的互动以及疫苗相关问题的信息来源的看法。在接受采访的女性中,对母体免疫的总体看法较为积极,许多人将疫苗接种与保护未出生的孩子联系起来。受访者列举了一些遵循免疫指南的原因,包括医疗保健专业人员的建议、有针对性的宣传活动以及积极使用疫苗接种卡或手册。没有报道母体疫苗存在障碍。一些使用私人医疗保健服务的女性报告说,在检查时没有被问及疫苗接种问题,这可能会对疫苗接种率产生不利影响。在接受采访的女性中,选择不接种疫苗的最常见原因是在寨卡病毒爆发期间出现的疫苗导致小头畸形的谣言。这项研究确定了重要的疫苗信心建设者。许多受访者批判性地思考了他们所收到的信息,将自己视为健康选择的决策者。母体免疫的一个突出障碍是一种将疫苗与小头畸形联系起来的谣言。据我们所知,这在文献中尚未有过报道,需要进一步调查这一问题的程度以及如何减轻这一问题。