Department of Gynecology with Center for Oncological Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany;
Department of Hepatology and Gastroenterology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Anticancer Res. 2021 Jul;41(7):3649-3656. doi: 10.21873/anticanres.15155.
BACKGROUND/AIM: Postoperative pancreatic fistula after distal pancreatectomy represents the most frequent procedure-related complication; however, a standard treatment is currently not available.
We herein report a case of postoperative pancreatic fistula after distal pancreatectomy and splenectomy in a patient affected by a platinum-sensitive ovarian cancer recurrence. The 59-year-old patient developed a pancreatic fistula on postoperative day 4. An endoscopic transgastric double-pigtail drainage was placed on postoperative day 13. The patient was discharged after 5 days and referred to adjuvant medical treatment. A month later, computed tomography revealed complete resolution of the fistula, the drainage was removed, and the patient continued chemotherapy. She recovered uneventfully at a 3-month follow-up.
EUS-guided drainage is a viable option in the management of postoperative pancreatic fistula, which can lead to a rapid resolution of peripancreatic fluid collections and to initiation of adjuvant chemotherapy with the slightest delay in ovarian cancer patients.
背景/目的:远端胰腺切除术后胰瘘是最常见的与手术相关的并发症;然而,目前尚无标准的治疗方法。
本文报告了一例铂类敏感卵巢癌复发患者行远端胰腺切除和脾切除术后发生胰瘘的病例。该 59 岁患者术后第 4 天发生胰瘘。术后第 13 天行经胃内镜双猪尾引流。患者 5 天后出院,并接受辅助治疗。1 个月后,计算机断层扫描显示瘘管完全愈合,引流管被移除,患者继续化疗。在 3 个月的随访中,患者恢复良好。
EUS 引导下引流是治疗术后胰瘘的一种可行选择,可迅速解决胰周积液,并在卵巢癌患者中以最短的延迟开始辅助化疗。