• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Low-dose Splenic Irradiation in Conjunction With Ruxolitinib to Provide Symptomatic Relief in Heavily Treated, Advanced Stage Myelofibrosis: A Case Series From a UK Tertiary Referral Center.低剂量脾脏照射联合芦可替尼用于为接受过大量治疗的晚期骨髓纤维化患者提供症状缓解：来自英国一家三级转诊中心的病例系列
Hemasphere. 2021 Jun 28;5(7):e611. doi: 10.1097/HS9.0000000000000611. eCollection 2021 Jul.
2
Fatal Disseminated Tuberculosis during Treatment with Ruxolitinib Plus Prednisolone in a Patient with Primary Myelofibrosis: A Case Report and Review of the Literature.鲁索替尼联合泼尼松治疗原发性骨髓纤维化患者期间发生致命播散性肺结核：一例报告及文献复习
Intern Med. 2018 May 1;57(9):1297-1300. doi: 10.2169/internalmedicine.9165-17. Epub 2017 Dec 27.
3
Myelosuppression toxicity of palliative splenic irradiation in myelofibrosis and malignant lymphoma.骨髓纤维化和恶性淋巴瘤中姑息性脾照射的骨髓抑制毒性
Hematology. 2015 May;20(4):203-7. doi: 10.1179/1607845414Y.0000000192. Epub 2014 Aug 17.
4
Splenic irradiation in myelofibrosis with myeloid metaplasia: a review.骨髓化生伴骨髓纤维化的脾区照射：综述
Blood Rev. 1999 Sep;13(3):163-70. doi: 10.1054/blre.1999.0110.
5
Usefulness of Low-Dose Splenic Irradiation prior to Reduced-Intensity Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Elderly Patients with Myelofibrosis.低剂量脾脏照射在老年骨髓纤维化患者造血干细胞移植的减低剂量预处理方案之前的应用价值
Case Rep Hematol. 2016;2016:8751329. doi: 10.1155/2016/8751329. Epub 2016 Oct 20.
6
The use of erythropoiesis-stimulating agents with ruxolitinib in patients with myelofibrosis in COMFORT-II: an open-label, phase 3 study assessing efficacy and safety of ruxolitinib versus best available therapy in the treatment of myelofibrosis.COMFORT-II研究中鲁索替尼联合促红细胞生成素刺激剂用于骨髓纤维化患者：一项评估鲁索替尼与最佳可用疗法治疗骨髓纤维化疗效和安全性的开放标签3期研究。
Exp Hematol Oncol. 2015 Sep 15;4:26. doi: 10.1186/s40164-015-0021-2. eCollection 2015.
7
Splenic irradiation as palliative treatment for symptomatic splenomegaly due to secondary myelofibrosis: a multi-institutional experience.脾照射作为继发于骨髓纤维化的有症状脾肿大的姑息治疗：多机构经验
J BUON. 2015 Jul-Aug;20(4):1132-6.
8
Splenic irradiation provides transient palliation for symptomatic splenomegaly associated with primary myelofibrosis: a report on 14 patients.脾照射可为原发性骨髓纤维化相关的有症状脾肿大提供短暂缓解：14例患者的报告
Int J Hematol. 2016 Apr;103(4):423-8. doi: 10.1007/s12185-016-1940-3. Epub 2016 Jan 20.
9
Splenic irradiation for symptomatic splenomegaly associated with myelofibrosis with myeloid metaplasia.对与骨髓化生的骨髓纤维化相关的有症状脾肿大进行脾脏照射。
Br J Haematol. 1998 Nov;103(2):505-11. doi: 10.1046/j.1365-2141.1998.00998.x.
10
Ruxolitinib in myelofibrosis: to be or not to be an immune disruptor.芦可替尼治疗骨髓纤维化：是否会成为一种免疫干扰剂。
Ther Clin Risk Manag. 2017 Feb 13;13:169-177. doi: 10.2147/TCRM.S121683. eCollection 2017.

本文引用的文献

1
Treatment of symptomatic splenomegaly with low doses of radiotherapy: Retrospective analysis and review of the literature.低剂量放疗治疗有症状的脾肿大：回顾性分析及文献综述
Tech Innov Patient Support Radiat Oncol. 2017 Sep 6;3-4:23-29. doi: 10.1016/j.tipsro.2017.08.002. eCollection 2017 Sep-Dec.
2
Current treatment algorithm for the management of patients with myelofibrosis, JAK inhibitors, and beyond.现行的骨髓纤维化患者管理治疗算法、JAK 抑制剂及其他。
Hematology Am Soc Hematol Educ Program. 2017 Dec 8;2017(1):489-497. doi: 10.1182/asheducation-2017.1.489.
3
A clinical-molecular prognostic model to predict survival in patients with post polycythemia vera and post essential thrombocythemia myelofibrosis.一个临床-分子预后模型，用于预测真性红细胞增多症后和特发性血小板增多症后骨髓纤维化患者的生存情况。
Leukemia. 2017 Dec;31(12):2726-2731. doi: 10.1038/leu.2017.169. Epub 2017 May 31.
4
Response to ruxolitinib in patients with intermediate-1-, intermediate-2-, and high-risk myelofibrosis: results of the UK ROBUST Trial.鲁索替尼治疗中危1级、中危2级和高危骨髓纤维化患者的疗效：英国ROBUST试验结果
Br J Haematol. 2015 Jul;170(1):29-39. doi: 10.1111/bjh.13379. Epub 2015 Mar 30.
5
Splenectomy in patients with myeloproliferative neoplasms: efficacy, complications and impact on survival and transformation.脾切除术治疗骨髓增殖性肿瘤：疗效、并发症及对生存和转化的影响。
Leuk Lymphoma. 2014 Jan;55(1):121-7. doi: 10.3109/10428194.2013.794269. Epub 2013 May 15.
6
Splenomegaly in myelofibrosis--new options for therapy and the therapeutic potential of Janus kinase 2 inhibitors.骨髓纤维化所致脾肿大——新的治疗选择和 Janus 激酶 2 抑制剂的治疗潜力。
J Hematol Oncol. 2012 Aug 1;5:43. doi: 10.1186/1756-8722-5-43.
7
How I treat splenomegaly in myelofibrosis.我如何治疗骨髓纤维化所致的脾肿大。
Blood Cancer J. 2011 Oct;1(10):e37. doi: 10.1038/bcj.2011.36. Epub 2011 Oct 7.
8
A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment).原发性骨髓纤维化患者生存的动态预后模型：国际骨髓增生性肿瘤研究和治疗工作组（IWG-MRT）的一项研究。
Blood. 2010 Mar 4;115(9):1703-8. doi: 10.1182/blood-2009-09-245837. Epub 2009 Dec 14.
9
How I treat symptomatic splenomegaly in patients with myelofibrosis.我如何治疗骨髓纤维化患者的症状性脾肿大。
Blood. 2009 May 28;113(22):5394-400. doi: 10.1182/blood-2009-02-195974. Epub 2009 Mar 30.
10
Clinical indications and biological mechanisms of splenic irradiation in chronic leukaemias and myeloproliferative disorders.脾脏照射在慢性白血病和骨髓增殖性疾病中的临床指征及生物学机制
Radiother Oncol. 2001 Mar;58(3):235-46. doi: 10.1016/s0167-8140(00)00316-9.

Low-dose Splenic Irradiation in Conjunction With Ruxolitinib to Provide Symptomatic Relief in Heavily Treated, Advanced Stage Myelofibrosis: A Case Series From a UK Tertiary Referral Center.

作者信息

Khan Alesia, Woodley Claire, Radia Deepti, Mikhaeel George N, Brady Jessica, Garcia Natalia Curto, Harrington Patrick, O'Sullivan Jennifer, Kordasti Shahram, Francis Yvonne, Asirvatham Susan, Ali Sahra, Sriskandarajah Priya, Saunders Jamie, de Lavallade Hugues, McLornan Donal P, Harrison Claire N

机构信息

Guy's International Centre of Excellence in Myeloid Disorders, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.

Department of Haematology, St. James' Hospital, Leeds, United Kingdom.

出版信息

Hemasphere. 2021 Jun 28;5(7):e611. doi: 10.1097/HS9.0000000000000611. eCollection 2021 Jul.

DOI:10.1097/HS9.0000000000000611
PMID:34235403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8240780/
Abstract
摘要