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骨化性鼓室成形术与非骨化性技术在胆脂瘤手术中的治疗效果:回顾性分析。

Treatment Outcome of the Bony Obliteration Tympanoplasty Versus Nonobliterative Techniques in Cholesteatoma Surgery: A Retrospective Analysis.

机构信息

Department of Otorhinolaryngology and Head and Neck Surgery, Erasmus Medical Center, Rotterdam, The Netherlands.

出版信息

Otol Neurotol. 2021 Oct 1;42(9):1366-1374. doi: 10.1097/MAO.0000000000003246.

Abstract

OBJECTIVE

In cholesteatoma surgery, obliteration of the mastoid and epitympanic space (bony obliteration tympanoplasty, BOT) is an increasingly used technique with low recurrent and residual cholesteatoma rates. While factors as the postoperative hearing level and infection rate are important for the patient as well, these outcome parameters are not frequently reported on in current literature. The objective of this study is to evaluate the recurrent and residual cholesteatoma rates of the BOT technique and nonobliterative canal wall up (CWU) and canal wall down (CWD) mastoidectomy in a large patient cohort. Secondary objectives were to evaluate the infection rate and hearing outcome for all three techniques.

DESIGN

Retrospective cohort study.

SETTING

Single-center study.

PATIENTS

All 337 adult patients (≥18 yrs) who underwent primary or revision cholesteatoma surgery between January 2013 and March 2019 were included.

MAIN OUTCOME AND MEASURES

Recurrent cholesteatoma rates, residual cholesteatoma rates, postoperative infections and other complications, hearing outcome.

RESULTS

The estimated combined rate of recurrent and residual cholesteatoma at 5 years follow-up was 7.6% in the BOT group, 34.9% in the CWU group, and 17.9% in the CWD group. The postoperative infection rate in the different groups ranged from 4.3% to 4.9%. The median gain in AC threshold level varied from 0.0 dB in the BOT and CWD group to 3.8 dB in the CWU group.

CONCLUSIONS

We show that cholesteatoma recurrence rates after the BOT technique in our clinic are significantly lower compared to CWU surgery. There were no differences in infection rate and no clinically relevant differences in postoperative hearing between the BOT, CWU, and CWD technique.

摘要

目的

在胆脂瘤手术中,乳突和鼓室空间的闭塞(骨性鼓室成形术,BOT)是一种越来越常用的技术,其复发和残留胆脂瘤的发生率较低。虽然术后听力水平和感染率等因素对患者也很重要,但这些结果参数在当前文献中并未经常报道。本研究的目的是评估 BOT 技术与非闭塞性鼓室盖向上(CWU)和鼓室盖向下(CWD)乳突切开术在大型患者队列中的复发和残留胆脂瘤率。次要目标是评估所有三种技术的感染率和听力结果。

设计

回顾性队列研究。

设置

单中心研究。

患者

所有 337 名成人患者(≥18 岁),他们在 2013 年 1 月至 2019 年 3 月期间接受了原发性或复发性胆脂瘤手术。

主要结果和测量

复发胆脂瘤率、残留胆脂瘤率、术后感染和其他并发症、听力结果。

结果

BOT 组、CWU 组和 CWD 组 5 年随访时复发和残留胆脂瘤的总估计率分别为 7.6%、34.9%和 17.9%。不同组的术后感染率在 4.3%至 4.9%之间。AC 阈值水平的中位数增益在 BOT 和 CWD 组为 0.0dB,在 CWU 组为 3.8dB。

结论

我们表明,我们诊所 BOT 技术后的胆脂瘤复发率明显低于 CWU 手术。感染率无差异,BOT、CWU 和 CWD 技术之间术后听力无临床相关差异。

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