Department of General Medicine, Nagoya University Hospital, Nagoya, Japan.
Center for Postgraduate Clinical Training and Career Development, Nagoya University Hospital, Nagoya, Japan.
Nagoya J Med Sci. 2021 May;83(2):269-276. doi: 10.18999/nagjms.83.2.269.
was first reported in 2000. Its characteristics such as isolation frequency, specimen types, and antimicrobial susceptibilities are poorly understood, because identification is difficult using conventional methods. We performed a retrospective observational study of 13 and 317 strains of and , respectively, isolated from consecutive patients at Nagoya University Hospital from January 2017 to December 2018. We analyzed patients' backgrounds, types of specimens, and antimicrobial susceptibilities. Antimicrobial susceptibilities were compared with those of . The frequencies of isolation of and were 3.9% and 96%, respectively. was not detected in specimens associated with mucous membranes, such as sputum and secretions from the craniocervical region, which were frequent for . was mainly detected in the skin (61.5%). All isolates were susceptible to anti-MRSA drugs, as well as to numerous other antibiotics, including those that are orally administered. For example, was significantly more susceptible to penicillin G, ceftriaxone, and ciprofloxacin than (respective susceptibilities: 66.7% vs 5.4%, 50.0% vs 4.0%, 66.7% vs 5.9%). There was no significant difference between meropenem and erythromycin, although susceptibility to each was relatively high (100.0% vs 31.7%, 50.0% vs 11.9%). was susceptible to numerous orally administered antibiotics and more susceptible to antimicrobial drugs than . was detected less frequently than and was infrequently detected in specimens associated with mucous membranes. These characteristics will aid the selection of optimal antimicrobial therapies.
该菌于 2000 年首次报道。由于常规方法鉴定困难,其分离频率、标本类型和药敏特点了解甚少。我们对名古屋大学医院 2017 年 1 月至 2018 年 12 月连续收治的 13 株和 317 株 、 进行了回顾性观察研究。分析患者背景、标本类型和药敏情况。比较药敏结果与 的药敏结果。 、 的分离率分别为 3.9%和 96%。 未在与黏膜相关的标本中检出,如痰和颅颈区分泌物,这是 的常见标本。 主要在皮肤中检出(61.5%)。所有 株均对抗 MRSA 药物以及其他多种抗生素敏感,包括口服抗生素。例如, 对青霉素 G、头孢曲松和环丙沙星的敏感性明显高于 (分别为 66.7%比 5.4%、50.0%比 4.0%、66.7%比 5.9%)。美罗培南和红霉素的敏感性虽无显著差异,但两者的敏感性均较高(100.0%比 31.7%、50.0%比 11.9%)。 对多种口服抗生素敏感,对药敏药物的敏感性高于 。 比 检出频率低,且较少在与黏膜相关的标本中检出。这些特征将有助于选择最佳抗菌治疗方案。